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Cyclosporine Blood Concentration (Pharmacokinetic Monitoring)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of cyclosporine, a medication used to prevent organ rejection after transplant or to treat certain autoimmune conditions, in your blood.

Quick summary

["Your cyclosporine level helps doctors monitor how well your body is responding to this medication and adjust doses as needed."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
78920-6
Short code
cycloSPORINE Bld IA-sCnc
Synonyms
cycloSPORINE Bld IA-sCnc
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Doctors order this test to ensure your cyclosporine levels stay within a safe range. Too little may mean your immune system isn’t suppressed enough, while too much could cause side effects like kidney damage or high blood pressure. It’s especially important after organ transplants or if you have conditions like rheumatoid arthritis or psoriasis.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for a few hours before your blood is drawn. Tell your healthcare provider about any medications, supplements, or recent illnesses that could affect results.

What Happens During the Test?

A healthcare professional will insert a small needle into a vein in your arm to draw blood. It usually takes a few minutes, and you may feel a brief pinch. The blood sample is then sent to a lab for analysis.

What Does the Test Result Mean?

Results are typically reported as a numeric value representing the cyclosporine concentration in your blood. Your doctor will interpret these results in relation to your medical history, symptoms, and other medications you’re taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Cyclosporine levels are critical for balancing immune suppression and avoiding toxicity. Abnormally high levels may lead to kidney damage, hypertension, or neurological issues, while dangerously low levels could increase infection risk. Regular monitoring is essential for long-term treatment.

Short name

Cyclosporine Level

Frequently asked questions

How often should I expect this test?
The frequency depends on your treatment plan. After an organ transplant, tests may be done weekly or monthly initially, then less often as your body adjusts. Your doctor will schedule follow-ups based on your specific needs and response to treatment.
What are common side effects of cyclosporine?
Common side effects include kidney problems, high blood pressure, tremors, nausea, or increased risk of infections. Severe side effects may include liver damage, seizures, or skin cancer. Always report any unusual symptoms to your healthcare provider.
Can diet or other medications affect my cyclosporine levels?
Yes, certain foods, supplements (like grapefruit juice), and other medications can alter cyclosporine absorption or metabolism. Always inform your doctor about all medications, herbs, or dietary changes before starting or adjusting treatment.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy