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Cyclosporine Blood Level (Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of cyclosporine, a medication used to prevent organ rejection after a transplant or to suppress immune responses in certain conditions, in your blood.

Quick summary

["Your cyclosporine level helps doctors monitor whether your dose is safe and effective."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
55805-6
Short code
cycloSPORINE Bld LC/MS/MS-mCnc
Synonyms
cycloSPORINE Bld LC/MS/MS-mCnc
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
0
Ref high
100
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
lc-ms-ms
CPT
83721
SNOMED
113079007
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors order this test to ensure your cyclosporine levels stay within a target range. Too little may mean your immune system isn’t properly controlled, while too much can cause serious side effects like kidney damage or high blood pressure. This test is especially important if you’ve had an organ transplant or take this medication for autoimmune diseases.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for a few hours before the test if your blood is drawn in the morning. Bring a list of all medications you’re taking, including cyclosporine, to your appointment.

How the Test Is Done

A healthcare provider will draw blood from a vein in your arm using a small needle. You may feel a slight pinch, but it usually doesn’t cause discomfort afterward. The blood sample is sent to a lab for analysis.

What the Results Mean

Results are typically reported as a numerical value representing the cyclosporine concentration in your blood. Your doctor will compare these results to your target range and adjust your medication dose if needed. Follow-up tests may be scheduled to monitor long-term levels.

Reference range

Optimal: <100 mg/dLN/A

Specimen: whole-blood

Fasting for 12-14 hours preferred. Water is permitted. Avoid alcohol for 24 hours before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Cyclosporine Level

Frequently asked questions

What are the typical reference ranges for this test?
Reference ranges can vary depending on your medical condition, the organ you’ve received (if applicable), and your doctor’s specific guidelines. Your doctor will provide your target range based on your needs. Too-high or too-low levels can affect how well your medication works or cause side effects.
How often should I get this test?
Your doctor will determine how often you need this test based on your treatment plan. For most transplant patients, tests may be done weekly or monthly at first, then less frequently as your levels stabilize. Always follow your doctor’s instructions.
Can I eat or drink before the test?
If your blood is drawn in the morning, you may need to fast for a few hours before the test. If your doctor has other instructions, follow them carefully. Avoid caffeine or alcohol before the test, as they may affect test results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy