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Cyclosporine in Blood (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of cyclosporine, a medication used to prevent organ rejection after a transplant or to treat certain autoimmune conditions, in your blood.

Quick summary

["Your cyclosporine level helps doctors monitor how well your body is responding to this medication."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
80561-4
Short code
cycloSPORINE DBS-mCnc
Synonyms
cycloSPORINE DBS-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

This test is done to check the amount of cyclosporine in your blood. Cyclosporine is an immunosuppressant medicine that must stay within a narrow range: too little may not prevent organ rejection or control your condition, while too much can cause serious side effects. Regular testing helps your doctor adjust your dose safely.

Doctors may order this test to ensure your cyclosporine levels stay within a safe range. This is especially important if you’re taking cyclosporine to manage conditions like organ transplants or autoimmune diseases. Too much or too little can affect how well your body heals or functions.

This test measures the level of cyclosporine, an immunosuppressant medication, in a sample of your blood. The result tells your care team how much of the drug is circulating in your body at the time of the blood draw, which helps them decide whether your current dose is keeping you within the safe, effective range your treatment requires.

The test measures the concentration of cyclosporine in your blood, which is measured in mass units per volume (e.g., micrograms per milliliter). This helps healthcare providers track your medication levels over time.

The test requires a blood sample, which is usually drawn from a vein in your arm at a clinic or laboratory. Timing is important, and many providers order a trough level, which is taken just before your next scheduled dose. Follow your provider's instructions about when to take your last dose and when to arrive for the blood draw, because timing can affect the result.

A blood sample is typically taken from a vein in your arm. The sample is sent to a lab where it is analyzed using a specialized method to detect cyclosporine.

Before the test, tell your healthcare provider about all prescription medicines, over-the-counter drugs, vitamins, and supplements you use, since many of them can change cyclosporine levels. You may be asked to wait to take your dose until after your blood is drawn. Unless you are told otherwise, eat and drink normally, stay well hydrated, and let the staff know if you bruise easily or have trouble with blood draws.

There are usually no special preparations needed for this test. You may feel slight discomfort from the needle, but it should go away quickly. If you’re on cyclosporine, your doctor may adjust your dose based on this test result.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Cyclosporine Level

Frequently asked questions

This test helps doctors determine if your medication levels are within the target range for your condition.
A high cyclosporine level may mean your dose is too strong, which raises the risk of kidney problems, high blood pressure, tremors, infections, and other side effects. A low level may mean the medicine is not strong enough to protect a transplanted organ or manage your condition. Your provider will use the result along with your symptoms and kidney function to adjust your dose if needed.
A high level may indicate your body is metabolizing the drug too quickly, which could reduce its effectiveness. A low level might mean your body is absorbing too much, increasing the risk of side effects.
How often you need this test depends on why you take cyclosporine, your dose, and how stable your levels are. Testing is usually frequent when treatment starts or after a dose change, sometimes weekly at first, and may then be spaced out to every few weeks or months once your levels are steady and your kidney function is normal. Always follow the schedule your provider gives you.
Your doctor will decide how often you need this test based on your treatment plan and how your body responds to cyclosporine. It may be done weekly, biweekly, or monthly, depending on your situation.
You can eat and drink normally before this test unless your doctor instructs otherwise. No special preparation is needed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy