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Cyclosporine Concentration in Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of cyclosporine, a medication used to prevent organ rejection or suppress the immune system, in your blood plasma.

Quick summary

["This helps doctors check if your dose is working properly."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
73427-7
Short code
cycloSPORINE ind plt IgG SerPl Ql FC
Synonyms
cycloSPORINE ind plt IgG SerPl Ql FC
Category
hematology
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test if you’re taking cyclosporine to manage a condition like organ transplant rejection, autoimmune diseases, or severe allergies. Regular checks help ensure the medication is at the right level to avoid side effects or treatment failure.

What Does the Result Mean?

Results are typically reported as a concentration in micrograms per milliliter (µg/mL). While reference ranges vary by lab and patient factors, low levels may indicate insufficient medication, while high levels could signal toxicity or improper dosing. Always discuss results with your healthcare provider.

How Is the Sample Collected?

A blood sample is drawn from a vein, usually in your arm. You may feel a small pinch, but it’s quick. The blood is then separated to analyze the cyclosporine concentration in the plasma portion.

What Should You Do Before the Test?

If you’re taking cyclosporine, avoid skipping doses or changing your medication without consulting your doctor. Also, inform your provider about all medications, supplements, or herbal products you’re using, as they may affect test results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Cyclosporine Levels Matter for Safety and Effectiveness

Short name

Cyclosporine Level

Frequently asked questions

Why do doctors monitor cyclosporine levels regularly?
Doctors monitor cyclosporine levels to balance its benefits and risks. Too little may mean your immune system isn’t suppressed enough, risking rejection or flare-ups of your condition. Too much can cause serious side effects like kidney damage, high blood pressure, or infections. Regular testing helps adjust your dose for optimal safety and effectiveness.
How often should I get this test?
Your doctor will determine your testing schedule based on your condition, medication regimen, and how well you’re responding to treatment. It may range from weekly to monthly checks, especially if you’re on a new dose or have a complex medical history.
Can I eat or drink before this test?
You can eat and drink normally unless your doctor specifies otherwise. Some medications or foods may affect test results, so always follow your provider’s instructions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy