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Cyclosporine in Plasma (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of cyclosporine, a medication used to prevent organ rejection or suppress the immune system, in your blood plasma.

Quick summary

["Your cyclosporine levels help doctors monitor how well your body is responding to this medication."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
16703-1
Short code
cycloSPORINE Plas-mCnc
Synonyms
cycloSPORINE Plas-mCnc
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Cyclosporine is a powerful drug that requires careful monitoring to avoid side effects like kidney damage or infections while ensuring it works effectively. Your provider may order this test if you’re taking cyclosporine for conditions like organ transplants, autoimmune diseases, or severe allergies.

What to Expect Before the Test

No special preparation is needed for this test. You may have a small needle inserted into your arm or vein to draw a blood sample. If you’re on cyclosporine, your provider will discuss timing with you—some patients take it with meals or on a schedule.

What the Results Mean

Results show your cyclosporine concentration in the plasma. High levels may indicate the drug isn’t being broken down properly, while low levels could mean it’s not working as intended. Your provider will compare these results to your treatment plan to adjust your dose if needed.

Common Uses and Who Needs It

This test is typically ordered for people taking cyclosporine for long-term conditions, such as after organ transplants (e.g., kidney, heart, liver), rheumatoid arthritis, or psoriasis. It’s also used in some cases of severe asthma or Crohn’s disease.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Cyclosporine Level

Frequently asked questions

How often should I get this test?
Your provider will determine the frequency based on your treatment plan, medication schedule, and how your body responds. Some patients need testing weekly or monthly, while others may only need it occasionally.
What happens if my levels are too high or too low?
If levels are too high, your provider may reduce your dose or switch to a different medication. If levels are too low, they might increase your dose or adjust timing (e.g., with meals) to improve absorption.
Can I eat or drink before this test?
You can eat and drink normally unless your provider specifies otherwise. Some medications (including cyclosporine) may be taken with food, so follow your provider’s instructions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy