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Cyclosporine Serum Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of cyclosporine, a medication used to prevent organ rejection after a transplant or to suppress immune responses in certain conditions, in your blood serum.

Quick summary

["Your cyclosporine level helps doctors monitor how well your body is responding to this medication."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
3521-2
Short code
cycloSPORINE Ser-mCnc
Synonyms
cycloSPORINE Ser-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors order cyclosporine levels to ensure the drug is at an effective concentration to prevent organ rejection or manage immune-related conditions without causing harmful side effects. It’s typically checked regularly during treatment to adjust the dose if needed.

What to Expect Before the Test

No special preparation is usually required. You may be asked to fast for a few hours before the test, but this depends on your doctor’s instructions. Bring any medications you’re taking to your appointment.

What the Results Mean

Results show the exact amount of cyclosporine in your blood. Low levels may mean the drug isn’t working well, while high levels can increase the risk of side effects. Your doctor will interpret these results in the context of your overall health and treatment plan.

Common Side Effects to Watch For

Cyclosporine can cause side effects like kidney problems, high blood pressure, or increased risk of infections. If you experience unusual fatigue, swelling, or signs of infection, contact your healthcare provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Cyclosporine levels are critical for balancing immune suppression and organ protection. Too little may lead to rejection or ineffective treatment, while too much can harm organs, kidneys, or increase infection risk. Regular monitoring helps prevent these risks.

Short name

Cyclosporine Level

Frequently asked questions

What triggers a cyclosporine test?
Tests are often scheduled before starting treatment, during regular follow-ups, or if you experience symptoms like nausea, high blood pressure, or unusual tiredness.
How often should cyclosporine levels be checked?
Frequency depends on your treatment plan—some patients need checks weekly or biweekly, while others may only need them monthly or less often.
Can lifestyle changes affect cyclosporine levels?
Yes, diet (e.g., grapefruit products), smoking, or certain medications can alter cyclosporine absorption or metabolism, so always inform your doctor about all supplements or changes.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy