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Cyclosporine concentration in serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of cyclosporine, a medication used to prevent organ rejection or suppress immune responses in certain conditions, in your blood serum.

Quick summary

["This test helps monitor your medication levels to ensure they stay within safe ranges for your treatment."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
15103-5
Short code
cycloSPORINE Ser-sCnc
Synonyms
cycloSPORINE Ser-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you’re taking cyclosporine to manage conditions like organ transplants, autoimmune diseases, or severe allergies. Regular monitoring helps prevent side effects and ensures the medication works effectively.

What Does the Result Mean?

Results are typically reported in mass concentration units (e.g., micrograms per milliliter). Low levels may indicate insufficient medication, while high levels could signal toxicity or improper dosing. Your provider will interpret results in the context of your treatment plan.

How Is the Test Performed?

A blood sample is drawn from a vein, usually in your arm. The serum portion is then tested using a specialized immunoassay method to measure cyclosporine concentration.

Common Reasons for Testing

This test is often done at regular intervals (e.g., weekly or monthly) to adjust medication doses, track compliance, or assess how your body processes the drug.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Monitoring Cyclosporine Levels

Short name

Cyclosporine Level

Frequently asked questions

What Are My Next Steps If My Results Are Abnormal?
If your results are outside the target range, your provider may adjust your cyclosporine dose, investigate potential interactions with other medications, or check for non-compliance. Follow-up tests will be scheduled as needed to stabilize your levels.
How Often Should I Expect This Test?
Frequency depends on your condition, dose, and healthcare provider’s guidelines. Some patients need testing weekly during initial treatment, while others may only need it monthly once stable.
Can I Avoid This Test by Taking My Medication Exactly as Prescribed?
While taking your medication consistently is crucial, cyclosporine absorption can vary due to factors like food, liver function, or other medications. Regular testing ensures your levels remain safe and effective.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy