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Cyclosporine trough blood concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of cyclosporine in your blood at a specific time to ensure your dose is properly adjusted for your treatment.

Quick summary

["Your cyclosporine levels help doctors balance effectiveness and side effects in organ transplant or autoimmune disease management."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
48597-9
Short code
cycloSPORINE Trough Bld IA-mCnc
Synonyms
cycloSPORINE Trough Bld IA-mCnc
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check if your cyclosporine dose is working as intended. Cyclosporine is used to prevent organ rejection in transplants or to control autoimmune conditions like rheumatoid arthritis or psoriasis. Trough levels are taken just before the next dose to monitor steady-state blood levels.

What Does the Result Mean?

Results help doctors determine if your dose needs adjustment. Too low levels may mean your immune system isn’t suppressed enough, while too high levels could increase side effects like kidney problems or infections. Your specific target range depends on your medical condition and other medications.

How Is the Sample Collected?

A blood sample is drawn from a vein, usually in your arm. You may feel a small pinch, but it’s quick and shouldn’t cause significant discomfort. The sample is sent to a lab for testing.

What Should You Do Before the Test?

Follow your doctor’s instructions carefully. Avoid taking cyclosporine right before the test, as it may affect the result. Also, inform your provider about all medications, supplements, or recent illnesses.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Cyclosporine Level (Trough)

Frequently asked questions

How often should I expect this test?
Your doctor will schedule this test based on your treatment plan. Typically, it’s done weekly or monthly at first, then adjusted as needed. Follow-up visits will determine how often you need testing.
What are common side effects of cyclosporine?
Common side effects may include kidney problems, high blood pressure, tremors, or increased risk of infections. Less common but serious side effects include liver damage or cancer. Your doctor will monitor for these while managing your dose.
Can I drink water before the blood draw?
Yes, you can drink water before the blood draw unless your doctor specifies otherwise. Hydration helps with the procedure, but avoid alcohol or caffeine in excess, as they may affect lab results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy