Cytology and Endocrine Hormone Profile (Brush Biopsy)
This test involves collecting cells or tissue from a brush biopsy and measuring hormone levels from a fluid sample, often used to evaluate conditions affecting both cellular and hormonal health.
["Assesses both cellular abnormalities and hormone balance in a single profile."]
Key facts at a glance
- LOINC
- 49050-8
- Short code
- Cyto Endocvx brush
- Synonyms
- Cyto Endocvx brush
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- cyto-stain
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test includes a **cytology component** (cell analysis) and **endocrine hormone measurements** from a fluid sample (likely serum or plasma). The cytology part may examine cells for abnormalities such as those found in cervical, endometrial, or other tissue samples. The endocrine part measures specific hormones, though the exact hormones aren’t specified in the compressed code. This combination helps diagnose conditions like hormonal imbalances, precancerous changes, or other systemic issues.
Why It’s Ordered
Doctors may order this test if you have symptoms or risk factors for conditions like **hormonal disorders** (e.g., thyroid, reproductive, or adrenal issues) or **precancerous cellular changes** (e.g., cervical dysplasia, endometrial abnormalities). It may also be used in research or specialized diagnostic scenarios where both cellular and hormonal data are relevant.
Sample Collection and Preparation
For the **brush biopsy**, a small sample of cells is collected using a brush, often during a procedure like a Pap smear or endometrial biopsy. For the **fluid sample**, blood (serum or plasma) is drawn and processed to extract hormones. The test may require fasting or specific timing depending on hormone levels being measured.
Common Uses and Conditions
This test is less commonly used in routine clinical practice but may be employed in **specialized settings**, such as fertility evaluations, endocrine research, or when investigating **mixed pathologies** (e.g., hormonal influences on cellular health). It’s not a standard screening test for most conditions.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Frequently asked questions
What does my test result mean?
How long will I need to wait for results?
Can I prepare for this test in any special way?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy