Endometrial Cytology (Cellular Analysis of the Uterine Lining)
This test examines cells collected from your uterine lining (endometrium) to check for abnormalities, such as signs of infection, inflammation, or precancerous changes.
["This test helps detect early signs of uterine health issues, including infections or potential cancer risks."]
Key facts at a glance
- LOINC
- 55604-3
- Short code
- Cyto Endometrium
- Synonyms
- Cyto Endometrium
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- cyto-stain
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is Endometrial Cytology Used For?
Endometrial cytology is primarily used to diagnose conditions affecting the uterine lining. It may be recommended if you have symptoms like abnormal vaginal bleeding, pelvic pain, or if you’re at higher risk for uterine abnormalities. This test can also help monitor conditions like endometrial hyperplasia or assess post-treatment outcomes in cases of known uterine issues.
How Is the Test Performed?
A healthcare provider collects cells from your uterine lining using a small brush or spatula during a procedure called a **dilation and curettage (D&C)** or sometimes through a simple swab during a pelvic exam. The cells are then analyzed under a microscope to identify any irregularities.
Preparation and Risks
No special preparation is needed, but you may be asked to avoid certain medications or procedures before the test. Common risks include mild cramping, bleeding, or infection, though serious complications are rare.
What Do Results Mean?
Results are interpreted by a pathologist and categorized into different classifications (e.g., normal, atypical, suspicious for malignancy). Abnormal findings may prompt further testing, such as additional biopsies or imaging, to investigate underlying causes.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Frequently asked questions
Why might my doctor recommend this test?
What happens if my test results are abnormal?
How often should I get this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy