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Liver Function Test: Bilirubin, Albumin, and Fibrinogen Profile (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures key substances in your blood that help assess liver health, including bilirubin (a waste product from red blood cells), albumin (a protein made by the liver), and fibrinogen (a blood-clotting protein).

Quick summary

["This test helps doctors check if your liver is working properly or if there may be an issue like inflammation, damage, or disease."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
31192-8
Short code
Cyto Liver FNA
Synonyms
Cyto Liver FNA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
136
Ref high
145
Critical range
120 N/A – 160 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
cyto-stain
CPT
84295
SNOMED
110741000
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

Bilirubin: This yellow pigment is produced when your body breaks down old red blood cells. High levels can indicate liver problems, gallbladder issues, or blood disorders. Albumin: A protein essential for keeping fluids in your blood vessels. Low levels may suggest liver disease or malnutrition. Fibrinogen: A protein involved in blood clotting. Low levels can signal liver dysfunction or bleeding disorders.

Why It Matters for Liver Health

Your liver performs hundreds of vital functions, including filtering toxins, producing proteins, and breaking down waste products. Blood tests like this one help identify early signs of liver damage, such as hepatitis, cirrhosis, or fatty liver disease, before symptoms appear.

When You Might Need This Test

Doctors may order this test if you have symptoms like jaundice (yellowing of skin/eyes), fatigue, abdominal pain, unexplained weight loss, or if you have a history of liver disease, alcohol use, or exposure to toxins.

Common Causes of Abnormal Results

Results may be affected by liver diseases (e.g., hepatitis, cirrhosis), blockages in bile ducts, certain medications, alcohol use, or genetic conditions. Other factors like malnutrition, infections, or metabolic disorders can also influence these levels.

Reference range

Adult: 136-145 mmol/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Liver Function Panel (Bilirubin, Albumin, Fibrinogen)

Frequently asked questions

What does a high or low level of bilirubin mean in this test?
High bilirubin may suggest liver disease, bile duct blockage, or red blood cell disorders. Low levels are less common but could indicate liver dysfunction or severe malnutrition. Your doctor will interpret results in the context of your overall health.
Why is albumin important in this test?
Albumin helps maintain fluid balance in your body. Low levels often indicate liver disease, kidney problems, or severe infections. Your doctor may use albumin levels to monitor liver function or guide treatment decisions.
How long does it take to get results from this test?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your doctor will discuss the findings with you during your follow-up visit.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy