Skip to content

Cytologic Examination of Prostatic Fluid (Fine Needle Aspiration)

Published: August 9, 2026Updated: August 16, 2026

This test analyzes cells collected from fluid obtained during a fine-needle aspiration of the prostate gland, often used to evaluate abnormal symptoms or suspicious findings.

Quick summary

["Helps diagnose prostate issues by examining cells from fluid aspirated during a procedure."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
31191-0
Short code
Cyto Prostate FNA
Synonyms
Cyto Prostate FNA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
136
Ref high
145
Critical range
120 N/A – 160 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
cyto-stain
CPT
84295
SNOMED
110741000
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may recommend this test if you have symptoms like persistent urinary issues, pain during urination, or other signs that suggest prostate abnormalities. It can also be used to investigate prostate enlargement, inflammation, or suspected cancer.

Procedure Overview

A needle is inserted into the prostate under imaging guidance to collect fluid. The fluid is then examined under a microscope to identify any abnormal cells, which may indicate conditions like infection, inflammation, or cancer.

What to Expect Before the Test

No special preparation is typically needed, but you may be asked to empty your bladder before the procedure. You might experience mild discomfort during the needle insertion, but it is usually brief.

What to Expect During the Test

You’ll likely lie on your back with your hips slightly elevated. The doctor will use imaging (like ultrasound) to guide the needle into the prostate. You may feel pressure or slight discomfort, but it shouldn’t be painful.

Reference range

Adult: 136-145 mmol/LN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Prostate Fluid Cytology

Frequently asked questions

This test can help identify abnormal cells in the prostate fluid, which may suggest conditions such as prostate cancer, infection, or benign prostatic hyperplasia (BPH). Early detection of abnormal cells can guide further treatment options.
The fluid collected during the procedure is sent to a lab where trained pathologists examine the cells under a microscope. They look for any irregularities, such as changes in cell shape, size, or clustering patterns that may indicate disease.
How long does it take to get results from this test?
Results from this test are usually available within a few days to a week, depending on the lab’s processing time. Your doctor will discuss the findings with you during a follow-up visit.
What are the possible risks or side effects of this procedure?
The procedure itself is generally safe, but possible minor risks include mild bruising, soreness, or infection at the needle insertion site. Rarely, complications like bleeding or nerve damage may occur, but these are uncommon.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy