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Cytochemical or Morphological Examination of Blood Cells (Bone Marrow Aspirate or Peripheral Blood Smear)

Published: August 9, 2026Updated: August 16, 2026

This test examines the shape, size, and appearance of your blood cells under a microscope. It helps identify any unusual cells that might suggest conditions like anemia, infections, or blood disorders.

Quick summary

["A microscopic look at your blood cells to spot potential health issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
55600-1
Short code
Cyto Prt
Synonyms
Cyto Prt
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
cyto-stain
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test involves analyzing blood or bone marrow samples for cellular details, including red blood cells, white blood cells, and platelets. Technicians observe features like cell shape, size, color, and any abnormalities such as fragments, inclusions, or unusual cell counts.

This test is often used to diagnose or monitor conditions like leukemia, lymphoma, anemia, or infections. It may also be part of routine checks for people with known blood disorders or those undergoing treatments that affect blood cells.

A small blood sample is drawn, typically from your arm. The sample is then spread thinly on a microscope slide and stained to highlight different cell types. The slide is examined under a microscope by a trained pathologist or hematologist.

Results are usually available within a few days, depending on lab processing times. Your healthcare provider will discuss the findings with you, including any abnormal findings that may require further testing or treatment.

This test helps detect or monitor conditions such as blood cancers (like leukemia or myeloma), immune system disorders, genetic blood disorders (like sickle cell disease), and infections that affect blood cells.

The main risk is the mild discomfort from the needle used to draw blood. Bone marrow aspiration (if performed) may involve a slightly deeper needle insertion and could cause temporary bruising or soreness.

If you have a bleeding disorder or are on blood-thinning medication, let your healthcare provider know before the test to ensure safe sample collection.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Blood Cell Morphology Check

Frequently asked questions

What does an abnormal blood cell count or appearance mean?
An abnormal finding may suggest a blood disorder, infection, or other health issue. Your doctor will review the results with you and may recommend additional tests or treatments based on the findings.
Frequency depends on your health condition and medical needs. Some people may need this test regularly if they have a chronic blood disorder, while others may only need it occasionally for monitoring.
For blood draws, you can usually eat and drink normally unless instructed otherwise. For bone marrow aspiration, follow your doctor’s specific instructions regarding fasting or preparation.
The needle insertion may cause slight discomfort, but most people describe it as mild to moderate. Bone marrow aspiration might feel slightly more intense due to deeper needle placement.
Some medications may affect blood cell counts or appearance. Always inform your healthcare provider about all medications, supplements, or treatments you’re taking before the test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy