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Salivary Gland Fine Needle Aspiration Cytology (FNA)

Published: August 9, 2026Updated: August 16, 2026

This test involves examining cells collected from a salivary gland using a fine needle to check for abnormalities such as benign growths, infections, or cancer.

Quick summary

["A simple procedure to diagnose potential salivary gland issues through cell analysis."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
31190-2
Short code
Cyto Salivary gland FNA
Synonyms
Cyto Salivary gland FNA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
136
Ref high
145
Critical range
120 N/A – 160 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
cyto-stain
CPT
84295
SNOMED
110741000
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is This Test For?

Salivary gland FNA cytology is used to evaluate suspicious lumps, swelling, or unusual growths in the salivary glands. It can help determine if a mass is benign (non-cancerous), infected, or malignant (cancerous). This test is often recommended when other imaging tests or physical exams suggest a need for further investigation.

Procedure Details

During the procedure, a healthcare provider will use a thin needle to collect cells from the salivary gland. A small amount of fluid or cells may be taken, and the sample is then sent to a lab for microscopic examination. The process usually takes a few minutes and may cause minor discomfort, but it is generally quick and not invasive.

Sample Collection and Preparation

The sample is collected directly from the salivary gland using a fine needle. The cells or fluid are then prepared on a microscope slide and stained to highlight different features under the microscope. This allows a pathologist to examine the cells for any abnormal patterns, such as those seen in infections, inflammation, or cancer.

When Might You Need This Test?

You may need a salivary gland FNA cytology if you have a persistent lump or swelling in your salivary glands, unexplained pain or discomfort, or if other tests (like ultrasound or MRI) suggest an abnormality. It is also used in cases where a biopsy of a salivary gland mass is required for a definitive diagnosis.

Reference range

Adult: 136-145 mmol/LN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test plays a crucial role in diagnosing salivary gland disorders by providing detailed information about the cellular makeup of the gland. Early detection of abnormalities can lead to timely treatment, improving patient outcomes. It helps differentiate between benign conditions, infections, and malignancies, guiding appropriate medical or surgical interventions.

Short name

Salivary gland FNA cytology

Frequently asked questions

How is the sample collected?
The sample is collected through a small, minimally invasive procedure where a fine needle is used to extract cells or fluid from the salivary gland. This is typically done in a doctor’s office or outpatient setting.
Is there any pain or discomfort during the procedure?
You may feel slight discomfort or pressure, but it is usually brief. Local anesthesia may be used to numb the area, reducing any pain. Most people tolerate the procedure well.
How long does it take to get results?
Results are typically available within a few days to a week, depending on the lab processing time and the complexity of the sample analysis.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy