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Cytology of Fine Needle Aspiration Fluid (FNA) for Tissue Analysis

Published: August 9, 2026Updated: August 16, 2026

This test examines cells collected from a small sample taken with a fine needle, often used to diagnose or monitor conditions affecting tissues, such as tumors or infections.

Quick summary

["A small needle sample helps doctors evaluate abnormal tissue growth or disease spread."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
31195-1
Short code
Cyto Soft Tiss FNA
Synonyms
Cyto Soft Tiss FNA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
136
Ref high
145
Critical range
120 N/A – 160 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
cyto-stain
CPT
84295
SNOMED
110741000
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is the Purpose of This Test?

Fine needle aspiration (FNA) involves inserting a thin needle into a suspicious lump, organ, or tissue to collect cells. These cells are then examined under a microscope to identify abnormalities, such as cancerous cells, inflammation, or other pathologies. This test is commonly used for diagnosing conditions like thyroid nodules, lymphomas, or breast cancer, as well as guiding treatment decisions.

How Is the Sample Collected?

The procedure is typically done in a doctor’s office or outpatient clinic. You may receive local anesthesia to numb the area. The needle is inserted carefully, and a small amount of fluid or cells is collected. The sample is then sent to a lab for analysis.

What Does the Test Involve After Collection?

The collected cells are processed and stained to highlight different features under a microscope. Pathologists review the sample to identify cell types, patterns, or abnormalities. The results help determine if there’s a disease, such as cancer, infection, or another condition requiring further action.

When Might This Test Be Ordered?

Your healthcare provider may recommend this test if you have a lump or abnormal growth, unexplained weight loss, persistent symptoms like pain or swelling, or if you’re at higher risk for certain diseases (e.g., cancer). It’s also used for monitoring known conditions or guiding treatment plans.

Reference range

Adult: 136-145 mmol/LN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

FNA Cytology

Frequently asked questions

Why do I need this test if I don’t have symptoms?
Even without obvious symptoms, this test can help detect abnormalities early, especially if you have a family history of certain diseases or are at higher risk. Early identification can improve treatment outcomes and reduce complications.
How long does it take to get results from this test?
Results typically take 1 to 3 business days, depending on the lab and complexity of the sample. Your doctor will discuss the findings with you during a follow-up visit.
Is this test painful?
The procedure itself is usually not painful due to local anesthesia. You may feel slight discomfort or pressure during the needle insertion, but most people describe it as mild.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy