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Cytology of Fine Needle Aspiration (FNA) Fluid from Superficial Tissue

Published: August 9, 2026Updated: August 16, 2026

This test examines cells collected from a small sample taken with a fine needle from a superficial tissue, often used to diagnose conditions like lumps, cysts, or infections.

Quick summary

["A small needle sample helps doctors assess tissue health or identify abnormalities quickly and safely."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
18503-3
Short code
Cyto Superf Tiss FNA
Synonyms
Cyto Superf Tiss FNA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
136
Ref high
145
Critical range
120 N/A – 160 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
cyto-stain
CPT
84295
SNOMED
110741000
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Fine needle aspiration (FNA) is a minimally invasive procedure that doctors use to take a small sample of cells from a lump or mass in your body. A thin, hollow needle is inserted into the area of concern to collect tissue or fluid for testing. This helps your healthcare provider determine what the lump is, such as whether it is benign or cancerous, without needing a larger surgical biopsy.

Fine needle aspiration (FNA) is a simple procedure where a thin needle extracts a small amount of fluid or cells from a tissue. This sample is then analyzed under a microscope to check for abnormalities, such as cancerous cells, infections, or inflammation.

Your doctor may recommend a fine needle aspiration (FNA) when you have a suspicious lump in places like your thyroid, breast, lymph nodes, or other soft tissues. It is often used to check for infection, inflammation, or tumors. The test helps guide treatment decisions by providing a clear diagnosis, especially when imaging tests such as ultrasound or CT scan show something that needs closer examination.

Your doctor may recommend this test if you have a noticeable lump, swelling, or an unexplained mass in the skin or superficial tissues. It’s also used for diagnosing conditions like thyroid nodules, cysts, or lymph node issues.

During a fine needle aspiration (FNA), you will lie or sit comfortably while the skin over the area is cleaned. A healthcare professional may use ultrasound guidance to place a very thin needle precisely into the lump. They draw back a small amount of cells or fluid into the syringe. The procedure is usually quick, often taking just a few minutes, and several samples may be taken for accurate results.

A healthcare provider will clean the area and use a fine needle to gently draw out fluid or cells. The sample is then sent to a lab for microscopic examination.

After the fine needle aspiration (FNA) sample is collected, it is sent to a laboratory where a pathologist examines the cells under a microscope. Your doctor will review the findings and explain what they mean for your health. Depending on the results, you might need further tests, a follow-up visit, or a treatment plan tailored to your condition.

The lab will analyze the cells under a microscope to identify any abnormal patterns, such as cancer cells, infections, or signs of inflammation. Results may take a few days to a week, depending on complexity.

Reference range

Adult: 136-145 mmol/LN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

FNA Cytology (Superficial Tissue)

Frequently asked questions

This test plays a key role in diagnosing conditions like benign or malignant tumors, infections, or autoimmune disorders by providing detailed cell-level information from superficial tissues.
How long will I have to wait for my fine needle aspiration (FNA) test results to be ready?
Results typically take 1–5 business days, but some complex cases may require additional time. Your doctor will contact you once they are ready.
Is this fine needle aspiration (FNA) test painful or will I feel discomfort during the procedure?
The procedure is usually quick and minimally uncomfortable, often described as similar to a small pinch. Local anesthesia may be used if needed.
No special preparation is needed, but follow any specific instructions your doctor provides, such as avoiding certain medications or fasting if required.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy