Transferrin with Iron Saturation (Serum)
This test measures how well your body can transport iron through the bloodstream by checking two key factors: transferrin (a protein that carries iron) and its iron saturation level.
["Helps assess iron availability and potential iron deficiency or overload in your blood."]
Key facts at a glance
- LOINC
- 90907-7
- Short code
- DAT IgG-Sp Reag p transf rx RBC Ql
- Synonyms
- DAT IgG-Sp Reag p transf rx RBC Ql
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 4.2
- Ref high
- 5.9
- Critical range
- 2 N/A – 7 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 85041
- SNOMED
- 900000000000003001
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like fatigue, pale skin, or unusual tiredness, or if they suspect conditions like iron deficiency anemia or hemochromatosis (iron overload). It can also be part of routine blood work or monitoring for certain medical conditions.
What to Expect Before the Test
No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if iron levels are being specifically measured. Bring any medications you’re currently taking to your appointment.
How the Test Works
A small blood sample is drawn from a vein in your arm. The sample is sent to a lab where it is analyzed to measure transferrin levels and iron saturation, which indicate how efficiently iron is being transported in your bloodstream.
What the Results Mean
Results help determine if your body is efficiently using iron for red blood cell production or if there’s an imbalance that needs attention. Low transferrin or iron saturation may suggest iron deficiency, while high levels could indicate conditions like hemochromatosis.
Reference range
Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A
No special preparation required. Stay well hydrated.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Transferrin iron saturation is a critical marker for diagnosing and managing iron-related disorders. Low levels often point to anemia or poor iron absorption, while elevated levels may signal excessive iron storage, which can lead to organ damage over time. Regular monitoring can help prevent complications from these conditions.
Short name
Transferrin Iron Index
Frequently asked questions
How long does it take to get results?
Can I eat or drink anything before the blood draw?
What are common symptoms if my transferrin iron saturation is abnormal?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy