Serum or plasma concentration of total protein by nephelometry
This test measures the amount of protein in your blood serum or plasma, which helps assess overall protein levels and identify potential issues like malnutrition, kidney disease, or liver problems.
["Your blood protein levels can signal health concerns that may need further evaluation."]
Key facts at a glance
- LOINC
- 52114-6
- Short code
- DAT IgG-Sp Reag RBCCo Ql
- Synonyms
- DAT IgG-Sp Reag RBCCo Ql
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 4.2
- Ref high
- 5.9
- Critical range
- 2 N/A – 7 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 85041
- SNOMED
- 900000000000003001
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why Is This Test Done?
Doctors may order a total protein test to check for conditions affecting protein synthesis, breakdown, or retention in the body. It can also help diagnose or monitor diseases like kidney disease, liver disease, multiple myeloma, or malnutrition.
What to Expect Before the Test
No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it involves drawing blood. Wear comfortable clothing and plan to stay near the testing site for a short time.
During the Test
A healthcare provider will insert a small needle into a vein in your arm to draw blood. You may feel a slight pinch, but the procedure is quick. The test itself involves analyzing the blood sample in a lab using nephelometry, a method that measures how much light scatters from proteins in the sample.
After the Test
After the blood draw, you may experience mild bruising, soreness, or swelling at the site. Apply gentle pressure to the area to help reduce discomfort. Avoid heavy lifting or strenuous activity for a few hours. Most people can return to their normal activities immediately.
Reference range
Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A
No special preparation required. Stay well hydrated.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Low total protein levels may indicate conditions such as malnutrition, liver disease, kidney disease, or excessive protein loss (e.g., from chronic diarrhea or kidney filtration issues). High levels could suggest dehydration, inflammation, or conditions like multiple myeloma, where abnormal protein production occurs. Monitoring protein levels helps guide treatment decisions and manage underlying health conditions.
Short name
Total Protein
Frequently asked questions
How long does it take to get results?
What does a low or high protein level mean?
Can I eat or drink before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy