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Serum or Plasma Immunoassay for Antibodies to Group B Streptococcus (GBS) – Quantitative

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of antibodies your body produces in response to Group B Streptococcus (GBS), a type of bacteria that can sometimes affect newborns during childbirth.

Quick summary

["Knowing your GBS antibody levels helps assess your risk of transmitting infection to your baby during delivery."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
1006-6
Short code
DAT IgG-Sp Reag RBC-Imp
Synonyms
DAT IgG-Sp Reag RBC-Imp
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
4.2
Ref high
5.9
Critical range
2 N/A – 7 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85041
SNOMED
900000000000003001
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test if you are pregnant, especially in the third trimester, or if you have a history of GBS infection. It helps determine whether you have enough antibodies to protect your baby from GBS-related complications, such as pneumonia or meningitis.

What to Expect Before the Test

You will likely have a simple blood draw from a vein in your arm. The process is quick and usually painless. No special preparation is needed, but inform your healthcare provider if you are on any medications or have allergies.

How the Test Results Are Used

Results help guide decisions about prenatal care, such as whether you need additional testing (like a vaginal swab) or if you may need antibiotics during labor to reduce the risk of passing GBS to your baby.

What the Results Mean

Higher antibody levels suggest your body has built up immunity to GBS. Lower levels may indicate a higher risk of transmitting the bacteria to your baby, prompting further evaluation.

Reference range

Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A

Specimen: serum

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

GBS Antibody Level

Frequently asked questions

Why might my GBS antibody test results be important?
GBS is a common bacteria that can cause serious infections in newborns. High antibody levels suggest your immune system has already fought off GBS, but low levels may mean your baby could be at risk if you deliver without antibiotics. Your doctor will discuss next steps based on your results.
What if my antibody levels are low?
If your results are low, your doctor may recommend additional testing (like a vaginal/rectal swab) to check for live GBS bacteria. If confirmed, you may receive antibiotics during labor to prevent infection in your baby. Follow-up care will be tailored to your specific situation.
How often should I get this test?
Most doctors recommend this test once during the third trimester (around 35–37 weeks). If you have a history of GBS infection or other risk factors, your provider may suggest testing earlier or more frequently. Always ask your healthcare team about your personal plan.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy