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Direct Antigen Antibody Test for Polysaccharide Antigens in Plasma (e.g., *Group B Streptococcus* or *Other Pathogens*)

Published: August 9, 2026Updated: August 17, 2026

This test checks for antibodies against certain sugar-like molecules (polysaccharides) found on the surface of certain bacteria, such as those that may cause infections like Group B Streptococcus (GBS). It helps identify if your immune system has detected and responded to these bacteria.

Quick summary

["This test supports early detection of bacterial infections by measuring immune system reactions to specific bacterial antigens."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
46274-7
Short code
DAT Poly-Sp Reag p transf rx RBC Ql
Synonyms
DAT Poly-Sp Reag p transf rx RBC Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
4.2
Ref high
5.9
Critical range
2 N/A – 7 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85041
SNOMED
900000000000003001
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects the presence of antibodies (proteins produced by your immune system) that target specific polysaccharides from certain bacteria. These polysaccharides are part of the bacteria’s outer structure and can trigger an immune response. The test uses a method called **nephelometry** (measuring light scattering) to quantify these antibodies in your plasma sample.

Why It’s Done

Doctors may order this test to evaluate immune responses in patients at risk for bacterial infections, such as newborns, pregnant individuals, or those with weakened immune systems. It can also be used in research or diagnostic screening for certain bacterial pathogens.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in your arm. The blood is processed to separate plasma (the liquid part containing antibodies) for testing. This test is performed on plasma, not whole blood.

Common Uses and Clinical Context

This test is often used in research settings or specialized diagnostic scenarios to assess immune responses to specific bacterial antigens. It may also be part of broader investigations into infections or immune system function.

Reference range

Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A

Specimen: serum

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Direct Antigen Antibody Test for Bacterial Polysaccharides

Frequently asked questions

What does a positive result mean?
A positive result means your immune system has detected antibodies against the polysaccharides tested, which could indicate prior exposure to the bacteria or an ongoing immune response. This is not a definitive diagnosis of infection but may guide further investigation in research or specialized settings.
Is this test used for routine infections like strep throat or pneumonia?
No, this test is not commonly used for routine infections. It is typically reserved for research, specialized diagnostic studies, or specific clinical contexts where antibodies against bacterial polysaccharides are being evaluated.
How long does it take to get results?
Results are typically available within 24 to 48 hours, depending on laboratory processing times and testing protocols. Your healthcare provider will discuss the results with you based on the clinical context.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy