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Serum/plasma quantitative protein electrophoresis (bromocresol purple method)

Published: August 9, 2026Updated: August 17, 2026

This test measures the distribution of different protein types in your blood, including albumin and globulins, using a specialized technique called bromocresol purple electrophoresis.

Quick summary

["Helps identify abnormal protein patterns that may signal conditions like liver disease, kidney problems, or multiple myeloma."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
1007-4
Short code
DAT Poly-Sp Reag RBC Ql
Synonyms
DAT Poly-Sp Reag RBC Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
4.2
Ref high
5.9
Critical range
2 N/A – 7 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85041
SNOMED
900000000000003001
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Proteins Are Measured?

Electrophoresis separates blood proteins based on their size and electrical charge. The test detects three main protein zones: albumin (fast-moving), alpha-globulins, beta-globulins, and gamma-globulins (slowest). Abnormal shifts in these zones can indicate underlying health issues.

Why This Test Is Done

Your healthcare provider may order this test to diagnose or monitor conditions affecting protein levels, such as liver disease (e.g., cirrhosis), kidney disease, or certain cancers like multiple myeloma. It’s also used to assess nutritional status or response to treatment.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in your arm. The blood is then processed into serum or plasma for testing. No special preparation is needed, but fasting may be advised depending on your specific order.

What Results Mean

Results show the relative amounts of each protein band. For example, a low albumin level or unusual spikes in globulins may signal problems. Your provider will interpret results in the context of your overall health and symptoms.

Reference range

Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A

Specimen: serum

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Protein Electrophoresis (Bromocresol Purple)

Frequently asked questions

Is this test painful?
The blood draw itself is minor and usually causes only mild discomfort. Most people feel no lasting pain, but some may experience slight bruising or soreness at the site. If you’re anxious, let your provider know about options like numbing cream.
How long will I need to wait for results?
Results are typically available within 24–48 hours, depending on lab processing times. Your provider will contact you once they’re ready, either by phone or through your health portal.
Can I eat or drink before this test?
No special diet is required unless instructed otherwise by your provider. However, if your test includes fasting (e.g., for other bloodwork), follow their guidance to avoid interfering with results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy