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Serum or plasma mass concentration of creatinine

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood. It helps assess kidney function.

Quick summary

["A key indicator of how well your kidneys are filtering waste from your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
38669-8
Short code
DDE Air-mCnc
Synonyms
DDE Air-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Creatinine levels help doctors check if your kidneys are working properly. High levels may suggest kidney problems, while low levels could indicate dehydration or other conditions. This test is often used alongside other kidney function tests.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw blood, which usually causes only mild discomfort. If you’re on a low-protein diet or have certain medications, let your doctor know before testing.

Common Causes of Abnormal Results

Elevated creatinine levels might be due to kidney disease, dehydration, or muscle breakdown. Lower levels could result from dehydration, overhydration, or certain medications. Always discuss your results with your healthcare provider.

When You Might Need This Test

Your doctor may order this test if you have symptoms like fatigue, swelling, or frequent urination, or if you have a history of kidney issues. It’s also part of routine check-ups for people with risk factors like diabetes or high blood pressure.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Creatinine Level

Frequently asked questions

How often do I need this test?
The frequency depends on your health. Healthy adults may get it every few years, while people with kidney concerns might need it more often. Your doctor will decide based on your medical history and symptoms.
Can diet affect my creatinine levels?
Yes, diet can influence creatinine levels. Eating a high-protein diet may temporarily raise levels, while dehydration can lower them. Always follow your doctor’s advice on diet and test timing.
What if my results are out of range?
If your results are abnormal, your doctor will discuss possible causes and next steps. They may recommend further tests or adjustments to your treatment plan.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy