Dimerized heavy chain of immunoglobulin M (IgM) in serum
This test measures the presence of abnormal heavy chain dimers of immunoglobulin M (IgM), a protein produced by the immune system. These dimers can indicate certain immune system disorders or conditions affecting protein structure.
["Abnormal IgM dimers may signal underlying immune or metabolic issues requiring further evaluation."]
Key facts at a glance
- LOINC
- 108010-0
- Short code
- D Dimer Msmt PPP
- Synonyms
- D Dimer Msmt PPP
- Category
- coagulation
- Sample
- plasma
- Container
- Lavender-top (EDTA) or Green-top (Heparin)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why is this test done?
Your healthcare provider may order this test if you have symptoms or conditions linked to abnormal protein structures in your blood, such as immune deficiencies, certain infections, or metabolic disorders. It may also be part of a broader evaluation for conditions like Waldenström macroglobulinemia or other monoclonal gammopathies.
What does the result mean?
Elevated levels of IgM heavy chain dimers may suggest an immune-related condition, while normal results do not rule out all possible causes. Your provider will interpret results in the context of your symptoms and medical history.
How is the test performed?
A blood sample is drawn from a vein, typically in your arm. The sample is processed to separate serum, where the IgM heavy chain dimers are measured using a specialized immunoassay technique.
What preparation is needed?
No special preparation is required for this test. You may eat and drink normally before the blood draw, unless instructed otherwise by your provider.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical significance: Elevated IgM heavy chain dimers can be associated with conditions such as Waldenström macroglobulinemia, certain infections, or metabolic disorders affecting protein folding. They may also appear in conditions where the immune system produces abnormal proteins. Further testing and clinical correlation are essential to determine the exact cause and appropriate treatment.
Short name
IgM heavy chain dimers (DIMERS)
Frequently asked questions
What does an abnormal result mean?
How often should I get this test?
Can lifestyle changes affect this test result?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy