D-dimer plasma mass concentration (quantitative)
This test measures the level of D-dimer, a protein fragment produced when blood clots break down. It helps assess the risk of blood clots or conditions like deep vein thrombosis or pulmonary embolism.
["D-dimer helps identify possible blood clot risks or rule them out in certain situations."]
Key facts at a glance
- LOINC
- 48058-2
- Short code
- D Dimer PPP IA.DDU-mCnc
- Synonyms
- D Dimer PPP IA.DDU-mCnc
- Category
- coagulation
- Sample
- plasma
- Container
- Lavender-top (EDTA) or Green-top (Heparin)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ia-ddu
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why Is This Test Done?
Your healthcare provider may order this test to check for signs of blood clots, especially if you have symptoms like swelling, pain, or shortness of breath. It can also be used to evaluate conditions like deep vein thrombosis (DVT) or pulmonary embolism (PE). Sometimes, it’s part of a screening or diagnostic process for other blood-related issues.
What Does a High or Low Level Mean?
A high D-dimer level often suggests recent clot formation, which can guide treatment decisions. However, a normal result doesn’t always mean you don’t have a clot—it may just mean no significant breakdown of clots was detected at the time of testing. False positives can occur, so results should be reviewed by a healthcare provider.
How Is This Test Performed?
A small blood sample is drawn from a vein, usually in your arm. The plasma portion is tested for D-dimer using a sensitive laboratory method to detect its presence.
What Are Common Causes of Abnormal Results?
Elevated D-dimer levels can be caused by active blood clots, certain cancers, infections, or other conditions that increase clot breakdown. Low levels may be normal or could indicate conditions like severe bleeding or certain blood disorders.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
D-dimer is primarily used as a screening or diagnostic tool to support the evaluation of suspected blood clots. While it’s not definitive on its own, it helps narrow down possibilities when combined with clinical findings and other tests. It’s also used in monitoring certain patients (e.g., those with cancer or recent surgery) to assess clot risks over time.
Short name
D-dimer
Frequently asked questions
What does a positive D-dimer test mean?
Can D-dimer levels change over time?
Is this test safe?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy