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D-dimer plasma mass concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of D-dimer, a protein fragment produced when blood clots break down. It helps assess whether you may have a blood clot or bleeding disorder.

Quick summary

["D-dimer helps guide decisions about further testing for blood clots or bleeding risks."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
111766-2
Short code
D Dimer SerPlBld IA.FEU-mCnc
Synonyms
D Dimer SerPlBld IA.FEU-mCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia-feu
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is D-Dimer?

D-dimer is a marker created when blood clots dissolve naturally in your body. It’s not a standalone diagnostic test but often used alongside other tests to support evaluations for conditions like deep vein thrombosis (DVT) or pulmonary embolism (PE).

Why Might You Need This Test?

Your doctor may order a D-dimer test if you have symptoms like leg swelling, chest pain, shortness of breath, or a history of clotting disorders. It can also help rule out certain bleeding risks or confirm the presence of clots in your bloodstream.

How Is the Test Performed?

A blood sample is drawn from a vein, usually in your arm. The blood is processed to separate plasma, where the D-dimer levels are measured using a specialized lab technique. Results are reported in mass concentration units.

What Do Results Mean?

High levels of D-dimer may suggest recent clot formation, while very low or absent levels may indicate no active clotting. However, results alone don’t diagnose conditions—they’re often part of a broader evaluation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

D-dimer

Frequently asked questions

Why was this test ordered?
Your doctor may have suspected a blood clot or bleeding issue based on symptoms, medical history, or other test results. D-dimer helps narrow down whether further imaging or tests are needed.
What are the typical reference ranges?
Reference ranges vary by lab and method. Low or undetectable levels often mean no active clotting, while elevated levels may indicate recent clot activity but aren’t definitive on their own.
Can lifestyle changes affect D-dimer levels?
D-dimer levels are influenced by clot activity, not typically by diet or exercise alone. However, conditions like pregnancy, recent surgery, or severe illness can temporarily alter results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy