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D-dimer (Plasma) – Fibrin Degradation Products

Published: August 9, 2026Updated: August 16, 2026

This test measures small protein fragments called D-dimer, which form when blood clots break down. It helps assess whether you’re at risk for blood clots or clot-related conditions.

Quick summary

["D-dimer helps diagnose or rule out blood clots, especially in deep vein thrombosis or pulmonary embolism."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
38898-3
Short code
D Dimer Titr PPP
Synonyms
D Dimer Titr PPP
Category
coagulation
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is D-Dimer Used For?

Doctors use D-dimer testing primarily to evaluate suspected blood clots. It can help determine if you have conditions like deep vein thrombosis (DVT) or pulmonary embolism (PE), where blood clots form in veins or the lungs. This test is often used alongside other tests or imaging to guide treatment decisions.

How Is the Test Performed?

A blood sample is drawn from a vein in your arm. The blood is processed to separate plasma, where the D-dimer fragments are measured using a sensitive immunoassay method. The test is usually done quickly, often within a few hours of drawing the blood.

When Might You Need This Test?

Your doctor may recommend a D-dimer test if you have symptoms like swelling, pain, or shortness of breath that could suggest a blood clot. It’s also used in certain situations to help confirm or rule out conditions like DVT or PE, especially when other tests or imaging are inconclusive.

What Are the Possible Results?

A high level of D-dimer suggests recent clot formation and breakdown, which may indicate a clot-related condition. A low or undetectable level usually means no significant clotting activity is present. Results alone don’t diagnose a condition—they’re used alongside other tests or clinical findings.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

D-dimer

Frequently asked questions

Why was I asked to have this test?
Your doctor may have ordered this test to check for blood clots in your veins or lungs, especially if you’ve had symptoms like swelling, pain, or breathing difficulties. It can also help monitor people at higher risk of clots, such as those with certain medical conditions or after surgery.
What does a high D-dimer result mean?
A high D-dimer result suggests there may be a recent clot in your body, but it doesn’t confirm the diagnosis on its own. Your doctor will use the result along with other tests, like imaging or symptoms, to make a full assessment. Sometimes, a high result can also be seen in other conditions, so follow-up is needed.
Can I do anything to prepare for this test?
No special preparation is needed for a D-dimer test. You can eat and drink normally before the blood draw. If you’re on blood thinners, let your doctor know before the test, as this may affect your results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy