D-dimer (Plasma) – Fibrin Degradation Products
This test measures small protein fragments called D-dimer, which form when blood clots break down. It helps assess whether you’re at risk for blood clots or clot-related conditions.
["D-dimer helps diagnose or rule out blood clots, especially in deep vein thrombosis or pulmonary embolism."]
Key facts at a glance
- LOINC
- 38898-3
- Short code
- D Dimer Titr PPP
- Synonyms
- D Dimer Titr PPP
- Category
- coagulation
- Sample
- plasma
- Container
- Lavender-top (EDTA) or Green-top (Heparin)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is D-Dimer Used For?
Doctors use D-dimer testing primarily to evaluate suspected blood clots. It can help determine if you have conditions like deep vein thrombosis (DVT) or pulmonary embolism (PE), where blood clots form in veins or the lungs. This test is often used alongside other tests or imaging to guide treatment decisions.
How Is the Test Performed?
A blood sample is drawn from a vein in your arm. The blood is processed to separate plasma, where the D-dimer fragments are measured using a sensitive immunoassay method. The test is usually done quickly, often within a few hours of drawing the blood.
When Might You Need This Test?
Your doctor may recommend a D-dimer test if you have symptoms like swelling, pain, or shortness of breath that could suggest a blood clot. It’s also used in certain situations to help confirm or rule out conditions like DVT or PE, especially when other tests or imaging are inconclusive.
What Are the Possible Results?
A high level of D-dimer suggests recent clot formation and breakdown, which may indicate a clot-related condition. A low or undetectable level usually means no significant clotting activity is present. Results alone don’t diagnose a condition—they’re used alongside other tests or clinical findings.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
D-dimer
Frequently asked questions
Why was I asked to have this test?
What does a high D-dimer result mean?
Can I do anything to prepare for this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy