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Serum Digoxin Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of digoxin, a medication used to treat certain heart conditions, in your blood.

Quick summary

["Digoxin levels help ensure you’re taking the right dose for your heart health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
109954-8
Short code
DENV IgG Msmt Ser
Synonyms
DENV IgG Msmt Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Digoxin is a medication often prescribed to manage heart rhythm disorders, such as atrial fibrillation or heart failure. Your doctor may order this test to check if your dose is working properly or if levels are too high, which could cause side effects like nausea, irregular heartbeat, or vision changes.

How the Test Works

A blood sample is taken from a vein in your arm. The lab uses a sensitive test to measure the exact amount of digoxin in your serum (liquid part of blood after clotting). This helps doctors monitor your response to treatment.

What to Expect Before the Test

There are no special preparations needed for this test. You may have a small bandage on the site where the blood was drawn, and you can resume normal activities afterward.

Possible Results and Interpretation

Results are typically reported in nanograms per milliliter (ng/mL). Your doctor will compare your result to your usual range and adjust your medication if needed. Too much digoxin can be dangerous, so it’s important to follow your doctor’s guidance.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Digoxin Level

Frequently asked questions

What does a high or low digoxin level mean?
High levels of digoxin can cause symptoms like nausea, vomiting, dizziness, or heart rhythm problems. Low levels may mean your medication isn’t working as intended, so your doctor might increase your dose. Always discuss any changes with your healthcare provider.
How often should I get this test?
Your doctor will determine how often you need this test based on your condition, medication, and response to treatment. Typically, it’s done every few weeks or months to monitor your levels.
Can I eat or drink before this test?
You can eat and drink normally before this test unless your doctor has instructed otherwise. No fasting is required.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy