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Serum Digoxin Concentration (Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of digoxin, a medication used to treat certain heart conditions, in your blood.

Quick summary

["Digoxin levels help ensure your medication dose is safe and effective."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
104383-5
Short code
DENV IgG sp1 Titr Ser IA
Synonyms
DENV IgG sp1 Titr Ser IA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you’re taking digoxin to manage heart rhythm issues (like atrial fibrillation) or heart failure. It helps check if your dose is too high or too low, which could affect your heart’s function or cause side effects like nausea or irregular heartbeat.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, usually drawn from a vein in your arm. The test is quick and done in a lab setting.

What the Test Results Mean

Results help your doctor adjust your digoxin dose if needed. Too much digoxin can cause toxic symptoms, while too little may mean your heart isn’t getting enough benefit. Your doctor will discuss these findings with you.

Common Uses and Conditions

This test is most commonly used in patients with heart conditions like atrial fibrillation, heart failure, or those taking digoxin long-term to monitor medication levels.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Digoxin is a cardiac glycoside that helps regulate heart rhythm by strengthening contractions. Abnormal levels can lead to toxicity (e.g., palpitations, vision changes) or insufficient dosing (e.g., worsening heart failure). Regular monitoring is critical for patients on long-term therapy.

Short name

Digoxin Level

Frequently asked questions

How often should I expect this test?
Your doctor will determine the frequency based on your digoxin dose, heart condition, and lab results. Some patients need monitoring weekly or monthly, while others may only need it occasionally.
What are typical symptoms if my digoxin level is too high?
Symptoms of digoxin toxicity may include nausea, vomiting, irregular heartbeat, confusion, or vision problems. If you experience these, contact your doctor immediately.
Can I eat or drink before the blood test?
You can eat and drink normally before the test, as it doesn’t require fasting. However, follow your doctor’s instructions if they specify any restrictions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy