Serum or Plasma Bile Acids (Total)

What Is Bile Acid Testing Used For?

Bile acids are produced by the liver and stored in the gallbladder. They help break down fats in the digestive system. High levels in the blood can sometimes indicate problems with bile flow, liver disease, or other metabolic conditions. This test may be ordered if you have symptoms like jaundice, unexplained fatigue, or digestive issues.

How Is the Test Performed?

A blood sample is taken from a vein in your arm. The sample is sent to a lab where bile acids are measured using a specialized immunoassay or enzymatic method. Results are reported as a concentration in arbitrary units.

What Might Affect Results?

Factors like recent meals, medications (especially bile acid-binding resins), liver disease, or bile duct obstructions can influence bile acid levels. Your healthcare provider will consider these when interpreting your results.

When Might You Need This Test?

Your doctor may recommend this test if you have symptoms like jaundice (yellowing skin/eyes), dark urine, pale stools, or unexplained abdominal pain. It may also be used to monitor conditions like primary biliary cholangitis or other liver or bile duct disorders.