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Hair Amino Acid Profile (Substance Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the levels of specific amino acids found in hair, which can help assess overall protein metabolism and potential nutritional deficiencies.

Quick summary

["Hair amino acid testing may provide insights into long-term protein balance and metabolic health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
50160-1
Short code
Deprecated Amino acids Hair-sCnc
Synonyms
Deprecated Amino acids Hair-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Hair Amino Acid Testing Used For?

Hair contains amino acids that reflect long-term dietary protein intake and metabolic processes. This test can help identify imbalances that may indicate conditions like protein malnutrition, metabolic disorders, or certain genetic conditions. It’s sometimes used in research or specialized clinical settings to evaluate systemic amino acid status over time, though it’s not a routine diagnostic tool for most health concerns.

How Is the Sample Collected?

A small sample of hair (typically a few strands or a section cut from the scalp) is collected. No special preparation is needed, but you may be asked to avoid certain hair treatments (like dyes or relaxers) before testing to ensure accurate results.

What Does the Test Measure?

The test analyzes the concentration of amino acids in hair, which can include essential and non-essential amino acids. These amino acids are building blocks of proteins and reflect how your body processes nutrients over time. Results may be reported as qualitative (qualitative assessment) or quantitative (concentration levels), depending on the lab’s method.

When Might This Test Be Ordered?

A healthcare provider may recommend this test in specialized cases, such as evaluating long-term nutritional status in individuals with chronic illnesses, monitoring metabolic conditions, or assessing potential genetic disorders related to amino acid metabolism. It’s less common for routine screening but may be considered in research or advanced clinical scenarios.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Hair amino acid testing can provide indirect clues about protein metabolism, but it’s not a direct measure of current blood levels. Elevated or low levels of specific amino acids in hair may suggest underlying metabolic imbalances, dietary deficiencies, or conditions like phenylketonuria (PKU) or other aminoacidopathies. However, results should always be interpreted in the context of clinical symptoms and other diagnostic findings. This test is not a substitute for standard blood tests or clinical evaluations.

Short name

Hair Amino Acid Test

Frequently asked questions

Why would my doctor order this test?
Your doctor might recommend this test if you have a suspected metabolic disorder, chronic malnutrition, or if they’re investigating long-term nutritional or genetic factors affecting your health. It’s often used in research or specialized care settings rather than for routine health checks.
What does a hair amino acid test involve?
You’ll provide a small hair sample (like a few strands or a section from your scalp). The lab analyzes the amino acids in the hair to assess protein metabolism over time. No special preparation is needed, but you may be asked to avoid hair treatments before testing.
Are there any risks or side effects?
There are no risks associated with providing a hair sample. The process is quick and painless, and there are no known side effects from the test itself.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy