Serum Amino Acid Profile (Electrophoresis)
This test measures the breakdown of amino acids in your serum using electrophoresis, a method that separates proteins and amino acids based on size and charge. It helps identify abnormal patterns that may suggest metabolic disorders.
["This test evaluates amino acid distribution in your blood for potential metabolic conditions."]
Key facts at a glance
- LOINC
- 49249-6
- Short code
- Deprecated Amino acids SerPl-Imp
- Synonyms
- Deprecated Amino acids SerPl-Imp
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
Electrophoresis separates amino acids into distinct bands based on their electrical charge and molecular weight. Each band represents a group of amino acids or related compounds. This method can detect imbalances that may indicate inherited or acquired metabolic issues.
Why It’s Performed
Doctors may order this test if you have symptoms like muscle weakness, fatigue, or unexplained metabolic disturbances. It’s also used in research or specialized diagnostic settings for conditions like amino aciduria or inborn errors of metabolism.
Sample Collection and Preparation
A blood sample is drawn from a vein, typically in the arm. The serum (liquid part of blood after clotting) is then processed and sent for electrophoresis. This process may take several hours to complete, depending on the lab’s workflow.
Interpreting Results
Results are presented as distinct bands or patterns on an electrophoresis gel. Abnormal patterns (e.g., extra bands, missing bands, or altered intensities) may indicate metabolic disorders. Your healthcare provider will compare these findings to your clinical symptoms and other test results.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Abnormal amino acid profiles can signal metabolic disorders such as amino acidopathies (e.g., maple syrup urine disease, tyrosinemia), urea cycle disorders, or other inherited conditions. These disorders can affect how your body processes nutrients, leading to complications like liver damage, seizures, or developmental delays. Early detection can guide treatment, such as dietary changes or enzyme therapy.
Short name
Amino Acid Electrophoresis
Frequently asked questions
When might I need this test?
What does the test involve?
Are there any risks or side effects?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy