Skip to content

Apolipoprotein B in Serum/Plasma (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of apolipoprotein B, a protein found in certain types of cholesterol particles in your blood.

Quick summary

["ApoB helps assess your risk of heart disease by evaluating cholesterol particle size and number."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
6772-8
Short code
Deprecated Apo B SerPl-mCnc
Synonyms
Deprecated Apo B SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Apolipoprotein B (ApoB) is a key protein in cholesterol metabolism. It’s found primarily in low-density lipoproteins (LDL), often called 'bad cholesterol,' but also in other particles like intermediate-density lipoproteins (IDL) and very low-density lipoproteins (VLDL). Measuring ApoB can give doctors a clearer picture of your cholesterol profile beyond just LDL cholesterol levels alone.

What It Measures

This test quantifies the total amount of ApoB in your blood, which reflects the number of cholesterol particles rather than just their size. Higher levels may indicate an increased risk of plaque buildup in your arteries.

How It’s Used

Doctors may order this test to evaluate cardiovascular risk, especially in patients with complex lipid profiles or those who don’t meet traditional LDL cholesterol guidelines. It can also help monitor treatment effectiveness for conditions like familial hypercholesterolemia.

What to Expect

A blood sample is drawn from a vein, usually in your arm. The test involves processing serum or plasma (the liquid part of blood after clotting) to measure ApoB levels. Results are typically ready within a few days.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Apolipoprotein B (ApoB)

Frequently asked questions

How does ApoB compare to LDL cholesterol?
Unlike LDL cholesterol, which measures the size and amount of individual particles, ApoB provides a more comprehensive count of all cholesterol-carrying particles in your blood. This can help identify patients at risk of heart disease even if their LDL levels appear normal.
What are the typical reference ranges?
Reference ranges vary by lab and patient factors. Your doctor will interpret results in the context of your overall health and medical history.
Can lifestyle changes affect ApoB levels?
Yes, diet, exercise, and smoking habits can influence ApoB levels. Changes like adopting a heart-healthy diet, increasing physical activity, or quitting smoking may help lower your ApoB and reduce cardiovascular risk.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy