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Bilirubin, Total (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of bilirubin in your blood. Bilirubin is a yellow pigment produced when red blood cells break down, and it helps your liver process waste products.

Quick summary

["Bilirubin helps identify liver function and bile flow issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
32767-6
Short code
Deprecated B burgdor25kD IgM Ser Ql
Synonyms
Deprecated B burgdor25kD IgM Ser Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Your doctor may order this test to check for liver problems, such as hepatitis, cirrhosis, or blockages in the bile ducts. It can also help diagnose conditions like hemolytic anemia, where red blood cells break down more quickly than usual.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw a blood sample. If you’re nervous, let your healthcare provider know so they can help make it more comfortable.

What the Results Mean

Higher than normal levels may suggest liver disease, bile duct issues, or red blood cell disorders. Lower levels might indicate liver problems that prevent bilirubin from being processed normally. Your doctor will discuss your results with you in detail.

Common Conditions Linked to Bilirubin Levels

Abnormally high bilirubin can be linked to conditions like jaundice (yellowing of the skin and eyes), gallstones, or certain cancers. Low levels are less common but may relate to liver diseases that disrupt bilirubin metabolism.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Total Serum Bilirubin

Frequently asked questions

How often will I need this test?
Your doctor will determine how often you need this test based on your health history, symptoms, and other tests. Some people may need it once, while others may need it regularly if they have ongoing liver or blood-related conditions.
What do I do if I have a mild reaction after the blood draw?
If you feel lightheaded or experience a small bruise or swelling at the injection site, apply gentle pressure to the area. If you have severe pain, dizziness, or signs of infection (like increased redness or fever), contact your doctor right away.
Can I eat or drink before this test?
You can eat and drink normally before this test unless your doctor has instructed otherwise. This test does not require fasting.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy