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Bilirubin, Total (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of bilirubin in your blood. Bilirubin is a yellow pigment produced when red blood cells break down, and it helps your liver process waste products.

Quick summary

["Bilirubin helps diagnose liver and bile duct problems, including jaundice and gallbladder issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
932-4
Short code
Deprecated Bld Prod Typ BBL
Synonyms
Deprecated Bld Prod Typ BBL
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test to check for liver disease, bile duct blockages, or conditions like hemolytic anemia, where red blood cells break down faster than usual. It can also help identify jaundice (yellowing of the skin or eyes) or monitor treatment progress for conditions affecting the liver or bile flow.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm to draw blood. If you’re nervous, let your healthcare provider know—they can help make it more comfortable.

What Happens During the Test

A healthcare professional will clean your arm and insert a needle to collect blood into a tube. The process usually takes a few minutes. You may feel a slight pinch, but it’s quick and painless.

Possible Side Effects

Common side effects include a small bruise, mild soreness, or slight swelling at the needle site. Rarely, you might feel lightheaded or dizzy if you stand up too quickly after the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated bilirubin levels can signal liver problems, such as hepatitis, cirrhosis, or bile duct obstructions. High levels may also indicate hemolytic anemia (where red blood cells are destroyed too quickly). Low levels are less common but could suggest liver disease or certain genetic conditions. Monitoring bilirubin helps track conditions like jaundice, gallstones, or metabolic disorders.

Short name

Total Bilirubin

Frequently asked questions

What causes bilirubin levels to rise?
Bilirubin levels can rise due to liver disease, bile duct blockages (like gallstones), or conditions where red blood cells break down faster than usual (such as hemolytic anemia). Other rare causes include certain genetic disorders or infections.
How long does it take to get results?
Results are typically available within 1 to 3 business days, depending on your lab’s processing schedule. Your doctor will discuss the findings with you during your follow-up visit.
Can I eat or drink before this test?
You can eat and drink normally before this test, as no special diet is required. However, if your doctor has specific instructions, follow them to ensure accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy