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Brain Magnetic Resonance Diffusion-Weighted Imaging (Diffusion-Weighted MRI) with Apparent Diffusion Coefficient (ADC) Mapping

Published: August 9, 2026Updated: August 16, 2026

This test uses MRI technology to assess how water moves within brain tissues. It helps identify areas where water movement is restricted, which may indicate conditions like stroke, tumors, or other abnormalities.

Quick summary

["MRI diffusion imaging helps doctors spot potential brain issues by measuring water diffusion patterns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
37436-3
Short code
Deprecated Brain MR Diff Wt
Synonyms
Deprecated Brain MR Diff Wt
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
mr
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test generates images that highlight differences in water diffusion within brain tissues. By comparing these patterns, healthcare providers can detect areas with restricted diffusion, often linked to acute conditions such as stroke or certain types of brain tumors.

How the Test Works

During the procedure, you lie on a table inside a strong magnetic field while exposed to radio waves. Specialized MRI sequences focus on diffusion-sensitive imaging, producing images that show how water molecules move through brain tissue.

Common Uses

This test is often used to diagnose or evaluate conditions such as ischemic stroke, brain tumors, abscesses, multiple sclerosis, or other pathologies affecting brain tissue integrity.

Preparation

No special preparation is needed. You may be asked to remove jewelry or clothing covering the head. If you have metal objects or implants, inform your doctor beforehand.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Brain MRI with Diffusion Imaging

Frequently asked questions

Why might my doctor order this test?
Your doctor may recommend this test to investigate unexplained neurological symptoms, evaluate suspected stroke, assess brain tumors, or diagnose conditions affecting brain tissue structure.
What are the typical findings?
Typical findings include areas of restricted diffusion (appearing dark on diffusion-weighted images) that may correspond to acute stroke, abscesses, or certain tumors. The appearance of these areas helps guide treatment decisions.
How long does the test take?
The MRI procedure itself typically takes about 30 to 60 minutes, including preparation and follow-up. The diffusion-weighted imaging portion is usually completed within 10 to 20 minutes.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy