Cystatin C, Serum Concentration
This test measures the level of cystatin C, a protein produced by all cells in the body that helps regulate cell growth. It’s often used to assess kidney function.
["Cystatin C helps evaluate kidney health and may support the diagnosis of kidney disease."]
Key facts at a glance
- LOINC
- 42142-0
- Short code
- Deprecated Brst Mam PC Bx CN guid
- Synonyms
- Deprecated Brst Mam PC Bx CN guid
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- mam
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why Is This Test Done?
Your doctor may order a cystatin C test to check how well your kidneys are working. It can be useful for monitoring kidney function, especially in people with conditions like diabetes or high blood pressure that can affect the kidneys. Cystatin C is also sometimes used alongside other tests to help determine if you have kidney disease or to guide treatment decisions.
How Is the Sample Collected?
A blood sample is taken from a vein, usually in your arm. You may feel a small pinch when the needle is inserted, but the procedure is quick. The blood is collected in a special tube and sent to the lab for testing.
What Do the Results Mean?
Higher than expected levels of cystatin C may indicate kidney problems or other health conditions. Lower levels might suggest kidney function is better than expected. Your doctor will interpret your results in the context of your overall health and other tests.
Common Conditions Monitored
Cystatin C is often used alongside creatinine tests to assess kidney function. It can help detect early signs of kidney disease, especially in people who don’t have symptoms yet. It’s also useful for monitoring kidney function in people with chronic conditions like diabetes or heart disease.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Cystatin C
Frequently asked questions
Why might my doctor want to check my cystatin C level?
How often should I get this test?
Can I eat or drink anything before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy