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Cayenne Pepper-Specific IgG Antibody (RAST), Qualitative

Published: August 9, 2026Updated: August 17, 2026

A qualitative test that looks for IgG antibodies directed against cayenne pepper. A positive result does not by itself confirm a symptomatic food allergy.

Quick summary

["This test can show prior immune exposure to cayenne pepper, but it cannot determine whether cayenne causes allergy symptoms."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
21450-2
Short code
Deprecated Cayenne IgG RAST Ql
Synonyms
Deprecated Cayenne IgG RAST Ql
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This laboratory test checks for IgG antibodies specific to cayenne pepper using RAST methodology. It is a qualitative test, meaning the result is reported as detected or not detected.

Why might I need this test?

It may be used to evaluate a possible immune response to cayenne pepper or to help investigate a suspected food-related reaction. Results should be interpreted alongside symptoms, dietary history, and other allergy testing.

How is the test performed?

A laboratory specimen is analyzed for cayenne-specific IgG antibodies using a RAST assay. The laboratory reports whether the antibodies are detected without providing a quantitative measurement.

How do I prepare for the test?

No special preparation is usually required unless your clinician or laboratory provides different instructions. Tell the laboratory about medicines, immune conditions, and recent immune-suppressing treatments, and do not stop prescribed medication without medical advice.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Detected cayenne-specific IgG may indicate previous exposure or an immune response to cayenne pepper. It does not establish that cayenne pepper is causing clinical allergy symptoms, and isolated IgG positivity should not be used alone to diagnose a food allergy.

Short name

Cayenne IgG antibody test

Frequently asked questions

Does a positive result mean I am allergic to cayenne pepper?
No. This test detects IgG antibodies, which may reflect exposure and do not necessarily indicate a symptomatic allergy. Your clinician should interpret the result with your history and examination.
Is this the same as testing for cayenne-specific IgE?
No. IgG and IgE are different antibody classes. IgE testing may be more relevant when evaluating immediate, IgE-mediated food allergy, although results still require clinical interpretation.
What should I do if I have symptoms after eating cayenne pepper?
Discuss the reaction with a healthcare professional, especially if it includes hives, swelling, wheezing, or difficulty breathing. Seek emergency care for severe breathing problems or swelling of the tongue or throat.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy