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White Blood Cell Count (WBC) with Differential Analysis (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the types and proportions of white blood cells in your blood, helping identify infections, immune responses, or other conditions affecting your blood cells.

Quick summary

["Understanding your white blood cell types can help diagnose health issues early."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
5489-0
Short code
Deprecated CD47 WBC-aCnc
Synonyms
Deprecated CD47 WBC-aCnc
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
4.5
Ref high
11
Critical range
2 N/A – 30 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85004
SNOMED
900000000000003002
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order a qualitative WBC differential when they suspect infections (like bacterial or viral), autoimmune diseases, or conditions affecting blood cell production. It’s also used to monitor treatment responses in certain cancers or blood disorders.

What to Expect Before the Test

No special preparation is needed. You’ll have a simple blood draw, usually from your arm, and the sample will be sent to a lab for analysis. The results are qualitative, meaning they describe the types of white blood cells rather than exact counts.

What the Results Mean

Results show the proportions of different white blood cell types (e.g., neutrophils, lymphocytes, monocytes). Abnormal patterns may indicate infections, inflammation, or other health concerns. Your doctor will interpret these results in the context of your symptoms and medical history.

Common Conditions Linked to WBC Differential Results

High or low proportions of certain white blood cells can signal conditions like infections (e.g., high neutrophils), autoimmune diseases (e.g., low lymphocytes), or blood disorders (e.g., abnormal monocytes). Chronic conditions like leukemia or lymphoma may also affect these counts.

Reference range

Adult: 4.5-11.0 x 10^9/LN/A

Specimen: whole-blood

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

WBC Differential (Qualitative)

Frequently asked questions

How long will I need to wait for my results?
Results are typically available within 24 to 48 hours, depending on lab processing times. Your doctor will contact you once they’re ready, especially if further testing or follow-up is needed.
Can I eat or drink before this test?
No special diet or fasting is required for this test. You can eat and drink normally as usual.
What does a ‘differential’ mean in this context?
A ‘differential’ refers to the breakdown of white blood cells into specific types (e.g., neutrophils, eosinophils, basophils, lymphocytes, monocytes). This helps doctors pinpoint whether a condition is related to a specific type of immune response or infection.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy