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C-reactive protein (CRP) – Serum/Plasma Concentration (High-Sensitivity)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of a protein called C-reactive protein in your blood. CRP is produced by your liver in response to inflammation, helping your body fight infections or injury.

Quick summary

["hs-CRP helps identify low-grade inflammation that may contribute to long-term health risks like heart disease."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
97865-0
Short code
Deprecated CHIKV IgG+IgM Pnl SerPl
Synonyms
Deprecated CHIKV IgG+IgM Pnl SerPl
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order hs-CRP to check for signs of inflammation, especially if you have risk factors for heart disease, diabetes, or other chronic conditions. It can also help monitor conditions like rheumatoid arthritis or after certain treatments.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a metabolic panel. Tell your provider about any medications or supplements you’re taking, as they may affect results.

What Happens During the Test?

A small needle will be used to draw blood from a vein in your arm. The blood will be sent to a lab for analysis. Results are typically available within 1–3 days.

What Do the Results Mean?

Results are reported in milligrams per liter (mg/L). Higher levels may indicate inflammation, while lower levels suggest reduced risk. Your provider will interpret results based on your health history and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated hs-CRP levels often signal chronic inflammation, which can be linked to cardiovascular disease, autoimmune disorders, or metabolic syndrome. While not a diagnostic test alone, it can guide preventive care or treatment adjustments.

Short name

hs-CRP

Frequently asked questions

What does a high hs-CRP level mean?
A high hs-CRP level suggests your body is experiencing inflammation, which may raise concerns for conditions like heart disease or arthritis. Your provider will discuss next steps based on your overall health.
Can lifestyle changes lower hs-CRP?
Yes! Reducing stress, improving diet (e.g., Mediterranean-style), staying active, and avoiding smoking can help lower inflammation over time. Always follow your provider’s advice for personalized guidance.
Is hs-CRP the same as a general inflammation test?
No, hs-CRP is a specific marker for inflammation. Other tests (like erythrocyte sedimentation rate or white blood cell count) may also be used to assess inflammation, depending on your symptoms and diagnosis.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy