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Clam-Specific IgG Antibody, Qualitative — RAST

Published: August 9, 2026Updated: August 17, 2026

A qualitative blood test for IgG antibodies to clam proteins using a RAST-type method. It is a historical, deprecated allergy test.

Quick summary

["This test detects antibodies to clam, but a positive result does not by itself confirm a clam allergy."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
21204-3
Short code
Deprecated Clam IgG RAST Ql
Synonyms
Deprecated Clam IgG RAST Ql
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This is a qualitative blood test that looks for IgG antibodies directed against clam proteins. The RAST designation refers to an older radioallergosorbent testing method, and this test is marked as deprecated and may not be available.

Why might I need this test?

It was historically used to evaluate a possible clam allergy. Food-specific IgG results do not reliably diagnose immediate, IgE-mediated food allergy, so current evaluation usually depends on the exposure history, targeted IgE blood testing, and sometimes skin-prick testing.

How is the test performed?

A blood sample is collected, and the separated serum is exposed to clam allergen in the laboratory. The assay then reports whether clam-specific IgG was detected. Many laboratories now use newer allergy-testing methods instead of RAST.

How do I prepare for the test?

No special preparation or fasting is generally required for this type of blood test. Follow any instructions provided by the laboratory, and consult the ordering clinician before changing food avoidance or allergy medication use.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A positive result indicates that IgG antibodies to clam were detected, which may reflect previous exposure or a general immune response. It does not by itself mean that a person has a clinically important clam allergy. A negative result also does not completely exclude allergy, and the result should be interpreted with the person's symptoms and exposure history.

Short name

Clam-specific IgG antibody (RAST)

Frequently asked questions

Does a positive result mean I am allergic to clams?
No. Clam-specific IgG can occur in people without a true allergy, so the result must be interpreted alongside symptoms and other appropriate allergy testing.
Can this test rule out a clam allergy?
No. A negative IgG result cannot exclude clam allergy, particularly an IgE-mediated reaction. A clinician may recommend targeted IgE testing or supervised skin-prick testing.
Should I avoid clams if this test is positive?
Ask the ordering clinician before making major dietary changes. A history of hives, swelling, wheezing, vomiting, or other immediate symptoms after eating clams warrants prompt medical advice.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy