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Cocaine concentration in serum (qualitative screening)

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of cocaine or its metabolites in your blood, often used to detect recent drug use.

Quick summary

["A simple blood test to screen for cocaine exposure."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
5940-2
Short code
Deprecated Cocaine Ser Ql
Synonyms
Deprecated Cocaine Ser Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like rapid heartbeat, confusion, or unusual behavior that could be linked to cocaine use. It may also be part of a broader evaluation for substance use, especially in medical or legal settings.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm to draw blood. If you’re nervous, let your provider know—they can help make it more comfortable.

What the Test Results Mean

A positive result means cocaine or its breakdown products were detected in your blood. A negative result means none were found. Remember, this is a screening test and may not show recent use if it’s very recent.

Common Reasons for False Results

False positives can happen if you’ve recently used other drugs, had recent medical procedures, or took certain medications. False negatives may occur if the test was done too soon after use or if the sample was handled improperly.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Cocaine Screen (Serum)

Frequently asked questions

How long does it take to get results?
Results are typically available within 1–2 business days, depending on your lab. If you need results urgently, your provider may request them faster.
Can I drink alcohol before this test?
Alcohol itself won’t affect this test, but it may mask symptoms of cocaine use. Avoid heavy alcohol use before testing if you’re concerned about recent drug exposure.
What if I have a history of drug use?
If you have a history of drug use, this test may be part of ongoing monitoring. Your provider can discuss how results fit into your overall care plan.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy