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Deprecated Cottonwood-Specific IgE, Qualitative (RAST)

Published: August 9, 2026Updated: August 17, 2026

A qualitative blood test for cottonwood-specific IgE antibodies, used to assess allergic sensitization. A positive result alone does not confirm that cottonwood causes your symptoms.

Quick summary

["A positive result suggests an immune reaction to cottonwood, but your symptoms and exposure history must also be considered."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
58021-7
Short code
Deprecated Cottonwood IgG RAST Ql
Synonyms
Deprecated Cottonwood IgG RAST Ql
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This qualitative test checks a blood sample for IgE antibodies directed against cottonwood, a tree whose pollen can cause seasonal allergies. RAST is an older type of allergy testing method, and this test entry is marked as deprecated.

Why might I need this test?

Your clinician may order it to evaluate possible cottonwood allergy, especially if you have sneezing, watery eyes, nasal congestion, wheezing, or other symptoms when exposed to cottonwood pollen.

How is the test performed?

A blood-based sample is analyzed for cottonwood-specific IgE using a RAST-type laboratory method. The result is reported as positive or negative rather than as a measured concentration.

How do I prepare for the test?

No special preparation is usually required. Tell your clinician about any antihistamines or other allergy medicines you are taking because they may affect the result; do not stop a prescribed medicine unless instructed.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A positive result indicates that the immune system has developed IgE antibodies to cottonwood, which is consistent with sensitization. It does not by itself prove that cottonwood is the cause of your symptoms or predict the severity of an allergic reaction. Your clinician should interpret the result alongside your history, examination, and other allergy tests.

Short name

Cottonwood IgE test

Frequently asked questions

Does a positive result mean I am allergic to cottonwood?
It indicates allergic sensitization to cottonwood, but symptoms and exposure history are also needed to determine whether it is clinically important.
Can this test tell me which symptoms are caused by cottonwood?
No. The test only reports whether cottonwood-specific IgE was detected and cannot identify the cause of individual symptoms.
Should I stop taking allergy medicine before the test?
Some medicines can reduce test results, so ask your clinician beforehand. Do not stop prescribed medication unless your clinician instructs you to do so.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy