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Nonionic Contrast Agent, Cerebrospinal Fluid (CSF) — Deprecated Test

Published: August 9, 2026Updated: August 16, 2026

A legacy test that detects nonionic contrast in cerebrospinal fluid, usually in connection with contrast-assisted spinal imaging.

Quick summary

["A positive result generally indicates exposure to contrast during spinal imaging rather than a disease process."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
42015-8
Short code
Deprecated C-spine Flr W Non-ionic contr
Synonyms
Deprecated C-spine Flr W Non-ionic contr
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
xr-fluor
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test examines cerebrospinal fluid (CSF) for a nonionic contrast agent used during certain imaging procedures. The test code is marked deprecated, meaning it is not part of routine current practice.

Why might I need this test?

It may have been ordered to confirm that a nonionic contrast agent was present in CSF after a myelogram or another spinal imaging procedure. Because this is a legacy test, the ordering clinician should confirm whether it is still available and appropriate.

How is the test performed?

A CSF sample is collected through lumbar puncture or another approved method and examined in a laboratory for nonionic contrast. The original test name does not specify the analytical method used.

How do I prepare for the test?

No specific preparation can be determined from the test code alone. Follow the ordering clinician's instructions, particularly if the sample will be obtained by lumbar puncture, and ask about positioning, local anesthetic use, and post-procedure care.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Detecting nonionic contrast in CSF generally reflects recent administration of the agent during spinal imaging. A result usually does not identify a disease by itself. If detection is unexpected, the ordering clinician may review recent procedures and possible sample contamination.

Short name

Nonionic contrast in CSF

Frequently asked questions

What does this test measure?
It measures whether a nonionic contrast agent is present in cerebrospinal fluid. Such agents may be used during myelography and related spinal imaging procedures.
Does a positive result mean I have a serious illness?
Usually not. In this context, a positive result most often indicates exposure to contrast during a recent imaging procedure rather than a disease process.
Is this test still routinely used?
The code is marked deprecated, so it is a legacy test. Confirm with the ordering clinician or laboratory whether it remains available and what current test, if any, is preferred.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy