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C-reactive protein (CRP) – Serum/plasma concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein, a protein your body produces in response to inflammation.

Quick summary

["CRP helps assess inflammation in your body."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
13222-5
Short code
Deprecated C trach C Ab SerPl-aCnc
Synonyms
Deprecated C trach C Ab SerPl-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Your doctor may order a CRP test to check for inflammation in your body. This simple blood test helps diagnose infections, monitor chronic conditions such as rheumatoid arthritis or lupus, and track how well your treatment is working over time. A high-sensitivity CRP test may also be used to help evaluate your risk of heart disease.

Doctors may order a CRP test to check for signs of inflammation, monitor conditions like infections, autoimmune diseases, or heart disease, or evaluate responses to treatments. It can also help identify risks for certain health issues before symptoms appear.

Very little preparation is needed for a CRP test. You can usually eat and drink normally and take your regular medications unless your doctor tells you otherwise. Let your healthcare provider know about any medicines, vitamins, or supplements you use, and mention any recent illness, injury, or surgery, since these can affect your CRP levels and your results.

No special preparation is needed, but you may be asked to fast for 8–12 hours before the test if it involves drawing blood from a vein. Wear comfortable clothing and let your healthcare provider know about any medications or medical conditions.

During a CRP test, a healthcare professional draws a small sample of blood, usually from a vein in your arm. They will clean the site, wrap a band around your upper arm, and insert a thin needle to collect the sample into a tube. The draw takes only a few minutes, and you may feel a quick pinch. A small bandage is placed on your arm afterward.

A healthcare professional will insert a small needle into a vein in your arm to draw blood. You may feel a slight pinch, but it usually doesn’t cause significant discomfort. The process takes about 5 minutes.

CRP results are reported in milligrams per liter (mg/L). Levels below 10 mg/L are generally considered normal, while higher readings can point to inflammation from an infection, injury, or a chronic condition such as arthritis. A very high CRP level may signal a serious infection that needs prompt care. Your doctor will interpret your result alongside your symptoms, medical history, and other tests.

Results are reported in milligrams per liter (mg/L). Higher than normal levels may indicate inflammation, infections, or other health concerns. Your doctor will interpret the results in the context of your overall health and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

CRP Blood Test

Frequently asked questions

CRP is a marker for inflammation, which can signal underlying health issues such as infections, autoimmune diseases (like rheumatoid arthritis), or conditions affecting the heart and blood vessels. Elevated levels may prompt further testing or adjustments to treatment plans.
A CRP test measures the level of C-reactive protein, a substance your liver makes, in your blood. When inflammation is present anywhere in your body, CRP levels rise, so this test helps your doctor look for infections and monitor conditions linked to inflammation.
A CRP test measures the concentration of C-reactive protein in your blood, a protein produced by your liver in response to inflammation or infection.
Most people receive their CRP test results within one to two days after the blood sample is collected, although the exact timing can vary depending on the laboratory that analyzes your sample and how quickly your doctor reviews and shares the report with you.
Results are typically available within 1–3 business days, depending on your lab and healthcare provider’s processes.
Yes, lifestyle factors like diet, exercise, stress, and smoking can influence CRP levels. Reducing inflammation through healthy habits may lower CRP, but results may take weeks to show.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy