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C-reactive protein (CRP) – Serum/Plasma Substance Concentration (scnc)

Published: August 9, 2026Updated: August 16, 2026

This blood test measures the level of C-reactive protein, a marker produced by your body in response to inflammation or infection.

Quick summary

["CRP helps track inflammation, guiding treatment for conditions like infections, autoimmune diseases, or after surgery."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
46287-9
Short code
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Synonyms
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Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ct
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order a CRP test to check for signs of inflammation in your body. This can help diagnose conditions such as infections (like pneumonia or appendicitis), autoimmune diseases (like rheumatoid arthritis), or monitor conditions like heart disease or certain cancers. It may also be used before or after surgery to assess risk.

What Does a High or Low CRP Level Mean?

A higher CRP level often indicates inflammation, but it doesn’t always pinpoint the exact cause. Very high levels may suggest severe infections or other serious conditions. Very low levels might mean your body isn’t responding to inflammation as expected, though this can also occur with certain medications or medical conditions.

Sample Preparation and Testing

This test uses a blood sample drawn from a vein, typically in your arm. The blood is processed to separate serum or plasma for testing. The CRP level is measured using an immunoassay method, which detects the protein in your blood.

What to Expect Before the Test

No special preparation is needed for this test. You can eat and drink normally before your blood draw. If you’re on blood-thinning medication, let your doctor know before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

CRP

Frequently asked questions

What does CRP measure?
CRP measures the concentration of C-reactive protein, a protein produced by the liver in response to inflammation. It’s a general marker of inflammation in the body, not specific to any one condition.
Can CRP levels change with diet or exercise?
Yes, lifestyle factors like diet, exercise, and stress can influence CRP levels. For example, a healthy diet and regular physical activity may help lower CRP levels, which is associated with reduced inflammation.
How often should CRP levels be checked?
Your doctor will determine how often to check your CRP levels based on your health condition and treatment plan. Regular monitoring may be needed for chronic conditions like heart disease or autoimmune disorders.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy