C-reactive protein (CRP) – Serum/Plasma Substance Concentration (scnc)
This blood test measures the level of C-reactive protein, a marker produced by your body in response to inflammation or infection.
["CRP helps track inflammation, guiding treatment for conditions like infections, autoimmune diseases, or after surgery."]
Key facts at a glance
- LOINC
- 46287-9
- Short code
- Deprecated CT XXX Bx needle guide
- Synonyms
- Deprecated CT XXX Bx needle guide
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ct
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why Is This Test Done?
Your doctor may order a CRP test to check for signs of inflammation in your body. This can help diagnose conditions such as infections (like pneumonia or appendicitis), autoimmune diseases (like rheumatoid arthritis), or monitor conditions like heart disease or certain cancers. It may also be used before or after surgery to assess risk.
What Does a High or Low CRP Level Mean?
A higher CRP level often indicates inflammation, but it doesn’t always pinpoint the exact cause. Very high levels may suggest severe infections or other serious conditions. Very low levels might mean your body isn’t responding to inflammation as expected, though this can also occur with certain medications or medical conditions.
Sample Preparation and Testing
This test uses a blood sample drawn from a vein, typically in your arm. The blood is processed to separate serum or plasma for testing. The CRP level is measured using an immunoassay method, which detects the protein in your blood.
What to Expect Before the Test
No special preparation is needed for this test. You can eat and drink normally before your blood draw. If you’re on blood-thinning medication, let your doctor know before the test.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
CRP
Frequently asked questions
What does CRP measure?
Can CRP levels change with diet or exercise?
How often should CRP levels be checked?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy