Skip to content

D-dimer (Plasma) - Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of D-dimer, a protein fragment produced when blood clots dissolve naturally in your body. It helps assess the risk of blood clots or clot-related conditions.

Quick summary

["D-dimer helps determine if you may have a clot-related issue, such as deep vein thrombosis or pulmonary embolism."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
30240-6
Short code
Deprecated D Dimer PPP-mCnc
Synonyms
Deprecated D Dimer PPP-mCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is D-Dimer Used For?

D-dimer is primarily used to evaluate whether you have a blood clot or are at risk of developing one. It can help guide decisions about further testing or treatment, especially in cases where you may have symptoms like leg swelling, chest pain, or shortness of breath that could suggest a clot.

When Might You Need This Test?

Your doctor may order a D-dimer test if you have symptoms of blood clots, such as unexplained leg swelling, pain, or redness, and if other tests are needed to confirm or rule out conditions like deep vein thrombosis (DVT) or pulmonary embolism (PE). It may also be used in certain diagnostic workups for unexplained bleeding or after a suspected clot event.

How Is the Test Performed?

A small blood sample is drawn from a vein, usually in your arm. The blood is then processed to measure the D-dimer levels in your plasma. This test is typically done in a laboratory using a sensitive detection method.

What Do Results Mean?

Results can vary based on your health and medical history. A high level of D-dimer often suggests recent clot formation or dissolution, while a low level may indicate no active clotting process. Your doctor will interpret the results in the context of your symptoms and other tests.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

D-dimer

Frequently asked questions

Why is this test important for my health?
D-dimer is important because it helps doctors quickly assess whether you have a clot-related condition. High levels may indicate a need for further testing or treatment to prevent complications like stroke or heart attack. However, it is not a definitive test on its own and should be used alongside other clinical findings.
Can a high D-dimer level always mean I have a clot?
Not necessarily. While elevated D-dimer is strongly suggestive of clot activity, other conditions like pregnancy, cancer, or certain infections can also cause elevated levels. Your doctor will consider your overall health and symptoms to make a diagnosis.
What if my D-dimer test is normal?
A normal D-dimer level means there is unlikely to be an active clot in your body, but it does not rule out all possibilities. If you have symptoms of a clot, further testing may still be needed to confirm or rule out conditions like DVT or PE.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy