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D. pteronyssinus-Specific IgG4 Antibodies, Qualitative — Radioallergosorbent Test (Deprecated)

Published: August 9, 2026Updated: August 16, 2026

This blood test detects IgG4 antibodies to D. pteronyssinus, a common house dust mite. It is marked as deprecated and may not be available.

Quick summary

["A positive result shows IgG4 antibodies to a house dust mite but does not by itself prove a clinical allergy."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
26422-6
Short code
Deprecated D pteronyss IgG4 RAST Ql
Synonyms
Deprecated D pteronyss IgG4 RAST Ql
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test looks for IgG4 antibodies directed against D. pteronyssinus, a type of house dust mite. It uses a radioallergosorbent testing method to provide a qualitative result and is marked as deprecated.

Why might I need this test?

It may have been used to evaluate immune exposure to house dust mites. Results are most useful when compared with allergy symptoms, exposure history, and other allergy tests.

How is the test performed?

A blood sample is collected and tested in the laboratory using the radioallergosorbent method to detect mite-specific IgG4 antibodies. The report is generally interpreted as positive or negative.

How do I prepare for the test?

No fasting is usually required for the blood draw. Because this test is deprecated, confirm its availability with the ordering clinician or laboratory.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A positive result indicates that IgG4 antibodies to D. pteronyssinus are present, which may reflect prior exposure or sensitization. Unlike allergen-specific IgE, IgG4 does not by itself establish a symptomatic allergy. A negative result does not completely exclude mite exposure or allergy.

Short name

D. pteronyssinus IgG4 (RAST)

Frequently asked questions

What is D. pteronyssinus?
It is a species of house dust mite found in many homes. People can become sensitized to proteins released by this mite.
Does a positive IgG4 result mean I am allergic?
Not necessarily. IgG4 can indicate exposure or immune sensitization, so the result must be interpreted with symptoms and other appropriate allergy testing.
Why is this test marked as deprecated?
The test is no longer routinely recommended or may no longer be available. Ask your clinician about current testing options if you have symptoms related to dust mites.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy