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Plasma Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your plasma. It helps assess how well your kidneys are filtering blood.

Quick summary

["A creatinine test helps check kidney function by measuring waste in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
5897-3
Short code
Deprecated dRVV Tme Plas Qn
Synonyms
Deprecated dRVV Tme Plas Qn
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
coag
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Creatinine is a byproduct of muscle breakdown and is normally filtered out of your blood by your kidneys. High levels may indicate reduced kidney function, while low levels could suggest overhydration or muscle loss. This test is often used alongside other kidney function tests to diagnose or monitor conditions like chronic kidney disease.

How the Test Works

A small blood sample is taken from your arm and sent to a lab. The lab uses a specialized method (likely enzymatic or nephelometric) to measure the concentration of creatinine in your plasma.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to avoid certain medications or foods that could affect results. Drink as usual unless instructed otherwise.

Possible Results and Interpretation

Results are typically reported in milligrams per deciliter (mg/dL). Your healthcare provider will interpret the results in relation to your overall health and any symptoms you may have.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Creatinine Level

Frequently asked questions

What could cause high creatinine levels?
High creatinine levels may be caused by kidney disease, dehydration, severe muscle damage, or conditions that reduce blood flow to the kidneys. It’s important to discuss any symptoms like swelling, fatigue, or changes in urine output with your doctor.
What could cause low creatinine levels?
Low creatinine levels may occur in people with very little muscle mass, overhydration, or certain liver or heart conditions. If you’ve recently lost weight or have a history of muscle loss, mention it to your healthcare provider.
How often should I get this test?
Your doctor will determine how often you need this test based on your health history, symptoms, and any ongoing conditions. Regular monitoring may be recommended if you have kidney disease or other health concerns.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy