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Group B Streptococcus (GBS) RNA Detection by Probe-Based Assay (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of genetic material from Group B Streptococcus (GBS) bacteria in your blood, which can help identify if you have an infection.

Quick summary

["GBS RNA testing supports early detection of bacterial infections in blood, aiding in timely medical decisions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
38383-6
Short code
Deprecated Enterococcus rRNA XXX Ql Prb
Synonyms
Deprecated Enterococcus rRNA XXX Ql Prb
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have symptoms like fever, chills, or unexplained infections, or if you’re at higher risk for bloodstream infections. It’s also used in research or specialized diagnostic contexts where GBS RNA detection is critical.

What to Expect Before the Test

No special preparation is needed. The blood sample is typically drawn from a vein in your arm. If you’re on blood-thinning medication, let your provider know before the test.

What the Test Results Mean

A positive result indicates the presence of GBS RNA, which may suggest an active infection. A negative result means no detectable GBS RNA was found in this sample. Results should be interpreted by your healthcare provider in the context of your symptoms and medical history.

Common Reasons for Testing

This test is often used in research studies, specialized diagnostic settings, or when monitoring for rare or specific bacterial infections. It’s not a routine screening test for GBS in most clinical practices.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

GBS RNA Screening

Frequently asked questions

How does this test differ from standard GBS culture methods?
Unlike traditional culture tests, which grow bacteria to identify them, this RNA-based test detects genetic material directly. It can be faster and more sensitive for detecting GBS in blood, but results may vary depending on the sample’s condition and testing platform.
Can this test detect GBS in other body fluids besides blood?
This specific test is designed for serum or plasma samples. If GBS RNA detection is needed in other fluids (e.g., urine, cerebrospinal fluid), a different test or method may be used.
What if I have a false-positive result?
False positives can occur with any test, including this one. Your healthcare provider will review your symptoms, medical history, and other test results to determine the best course of action. Follow-up testing or additional evaluation may be recommended if needed.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy