Genetic analysis for hereditary bleeding disorders (e.g., factor V Leiden mutation)
This test checks for specific genetic mutations linked to inherited blood clotting issues, such as those causing abnormal bleeding tendencies.
["Identifies genetic risks for bleeding disorders that may affect blood clotting function."]
Key facts at a glance
- LOINC
- 106130-8
- Short code
- Deprecated HBD gene Bld/T
- Synonyms
- Deprecated HBD gene Bld/T
- Category
- chemistry
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- molgen
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test examines DNA samples from your blood to detect mutations in genes associated with hereditary bleeding disorders. These mutations can alter how your blood clots, sometimes leading to conditions like von Willebrand disease or factor deficiencies.
Why It Might Be Ordered
Your healthcare provider may recommend this test if you have a family history of unexplained bleeding, recurrent bruising, excessive bleeding during procedures, or if you’re considering pregnancy and have a history of bleeding disorders.
How the Test Works
A small blood sample is taken and analyzed in a lab to identify specific DNA changes (mutations) in genes responsible for blood clotting. Advanced techniques like next-generation sequencing are used to scan for these variations.
Preparation and Process
No special preparation is needed, but you may be asked to fast for 8–12 hours before the blood draw if instructed. The process involves a simple venipuncture (blood draw) and results are typically available within 1–2 weeks.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
Hereditary Bleeding Disorder Genetic Test
Frequently asked questions
If mutations are found, they may explain why you or a family member experience unusual bleeding or clotting problems. Early detection can guide treatment options, such as avoiding certain medications or lifestyle adjustments to manage symptoms.
This test is not covered by all insurance plans, so check with your provider about costs and coverage before scheduling.
Will I need to fast for this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy